Informations générales (source: ClinicalTrials.gov)
Efficacy of Non-instrumental Pleural Chest Physiotherapy (KRP-NI) in Initial Management of Infectious Pleural Effusion (KINEPANCH)
Interventional
N/A
Hôpital NOVO (Voir sur ClinicalTrials)
juin 2019
mars 2025
21 septembre 2024
The main purpose of this study is to assess efficacy of non instrumental pleural chest
physiotherapy on the recovery of respiratory function, at hospital discharge or 15 days
after beginning the pleural chest physiotherapy, compared to physiotherapy with standard
mobilization, in patients with infectious pleural effusion, who have received usual
medical treatment.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL NOVO | MONTRELAY | 04/07/2024 11:05:00 | Contacter | ||
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| AP-HP - Hôpital Bichat | Sonia Hassan | Contact (sur clinicalTrials) | |||
| CHI DE CRETEIL | Géraldine CADUERET | Contact (sur clinicalTrials) | |||
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Centre Hospitalier de Cholet - 49 300 - Cholet - France | Cynthia GUEGAN | Contact (sur clinicalTrials) | |||
| Centre Hospitalier de Dunkerque - 59240 - Dunkerque - France | Lionel Pitau | Contact (sur clinicalTrials) | |||
| Centre Hospitalier Régional d'Orléans - 45067 - Orléans - France | Joao Amaral | Contact (sur clinicalTrials) | |||
| Centre Hospitalier Universitaire de Grenoble - 38700 - Grenoble - France | Jordi Fabregat | Contact (sur clinicalTrials) | |||
| Groupe Hospitalier de la Rochelle - 17000 - La Rochelle - France | Alba Regueira Crespo | Contact (sur clinicalTrials) | |||
| Hôpital de la Cavale Blanche - 29200 - Brest - France | Marion Goret | Contact (sur clinicalTrials) | |||
| Hôpital Dupuytren - 87000 - Limoges - France | Dominique Pejoan | Contact (sur clinicalTrials) | |||
| Hôpital Victor Dupuy - 95100 - Argenteuil - France | Christopher Vion | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Centre Hospitalier Henri Duffaut - Avignon - 84 000 - Avignon - France | Quentin GONNET | Contact (sur clinicalTrials) | |||
| Centre Hospitalier Universitaire Angers - 49000 - Angers - France | Sophie Baudoin | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- ≥ eighteen years old
- to be hospitalized for an infectious pleural outpouring
- to have a liquid pleural outpouring diagnosed by echography or to scan thoracic
- presence of a Exudate according to the criteria of Light, to have at least criteria:
- The ratio of pleural fluid protein to serum protein is greater than 0.5
- The ratio of pleural fluid Lactate dehydrogenase (LDH) and serum LDH is greater
than 0.6
- The rate of pleural fluid LDH is > 2/3 upper limit of normal serum LDH of the
laboratory concerned
- presence of at least two of the following criteria:
- fever higher or equal 38°C (100.4°F)
- thoracic pain
- purulent sputum
- purulent pleural effusion at the time of the exploring pleural puncture
- hearth of crackling to the sounding
- Inflammatory syndrome (CRP>15 mg/l and/or White blood cell >10 000 /mm3)
- no known radiological hearth before
- Having undergone an evacuation gesture going back to less forty-eight hours:
evacuation pleural puncture or repeated pleural punctures or pleural drainage
allowing the evacuation of at least 100cc of pleural fluid
- Informed and having given its free, lit and express assent
- Patients with affiliation to the social security system
- ≥ eighteen years old
- to be hospitalized for an infectious pleural outpouring
- to have a liquid pleural outpouring diagnosed by echography or to scan thoracic
- presence of a Exudate according to the criteria of Light, to have at least criteria:
- The ratio of pleural fluid protein to serum protein is greater than 0.5
- The ratio of pleural fluid Lactate dehydrogenase (LDH) and serum LDH is greater
than 0.6
- The rate of pleural fluid LDH is > 2/3 upper limit of normal serum LDH of the
laboratory concerned
- presence of at least two of the following criteria:
- fever higher or equal 38°C (100.4°F)
- thoracic pain
- purulent sputum
- purulent pleural effusion at the time of the exploring pleural puncture
- hearth of crackling to the sounding
- Inflammatory syndrome (CRP>15 mg/l and/or White blood cell >10 000 /mm3)
- no known radiological hearth before
- Having undergone an evacuation gesture going back to less forty-eight hours:
evacuation pleural puncture or repeated pleural punctures or pleural drainage
allowing the evacuation of at least 100cc of pleural fluid
- Informed and having given its free, lit and express assent
- Patients with affiliation to the social security system
- Patient having undergone a thoracotomy or thoracoscopy in the six previous months
- Patient having a pneumothorax
- Patient reached of a tuberculosis
- Patient unable to carry out a measurement of the vital capacity by portable
spirometer at the inclusion
- Pregnant woman or nursing
- Patient having a life expectancy lower than three months
- Proven or suspected pleural neoplasia disease
- Patient hemodynamically unstable
- Patient having a respiratory insufficiency requiring the introduction of an
artificial ventilation
- Patient carrying a chronic respiratory insufficiency under non-invasive ventilation
with the long course
- Patient unable to carry out the exercises of physiotherapy (problem of communication
and/or comprehension and/or physical inaptitude)
- Patient transplanted of a solid body, allograft or autograft of hematopoietic stem
cells
- Patient with a seropositivity for the known HIV and cluster of differentiation 4
(CD4) <250/mm3