Informations générales (source: ClinicalTrials.gov)
Study of the Effects of Muscular Activity on Iron Metabolism: A Pilot Study on Healthy Volunteers
Interventional
N/A
Rennes University Hospital (Voir sur ClinicalTrials)
septembre 2006
29 juin 2024
The aim of this study is to evaluate the effect of muscular exercise on iron metabolism
in healthy volunteers. Fourteen healthy male subjects will have to pedal on an ergocycle
for 45 minutes, and urine and blood samples will be collected regularly to measure
hemojuvelin, hepcidin, iron and transferrin levels.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Unité de Biologie et Médecine du Sport - Hôpital de Pontchaillou - 35033 - Rennes - France | Pierre Rochcongar, MD | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Service des Maladies du Foie - Hôpital de Pontchaillou - 35033 - Rennes - France | Pierre Brissot, MD | Contact (sur clinicalTrials) | |||
Critères
Homme
Inclusion Criteria:
- Male individuals aged between 18 and 40 years old
- Body mass index (BMI) between 18 and 25
- Normal at clinical examination
- Normal biological variables
- Written informed consent
- Male individuals aged between 18 and 40 years old
- Body mass index (BMI) between 18 and 25
- Normal at clinical examination
- Normal biological variables
- Written informed consent
- Mutation C282Y of the HFE gene
- Iron metabolism abnormality
- Inflammatory syndrome
- Chronic pathology or ongoing treatment
- Tobacco smoking, alcohol consuming more than 30g/day
- History of transfusion or blood-giving within 3 months
- Positive serology for hepatitis B virus (HBV), hepatitis C virus (HCV) or HIV.