Informations générales (source: ClinicalTrials.gov)
Evaluation of Extracorporeal Photochemotherapy in Children and Young Adults With Refractory Acute Graft Versus Host Disease After Allogeneic Stem Cell Transplantation
Interventional
Phase 2
University Hospital, Clermont-Ferrand (Voir sur ClinicalTrials)
juin 2009
décembre 2012
29 juin 2024
Purpose : to evaluate the efficacy of ECP in children with refractory acute GVHD This
study addresses patients with persistent GVHD after steroid and/or monoclonal antibody
therapy
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU Clermont-Ferrand - 63000 - Clermont-Ferrand - France | Patrick Lacarin | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- 0 to 30 years
- Acute GVHD refractory to steroids (disease progression after 2 days or absence of
response after 4 days) and/or second line therapy (absence of response after 8 days)
- patient consent and/or parent consent
- 0 to 30 years
- Acute GVHD refractory to steroids (disease progression after 2 days or absence of
response after 4 days) and/or second line therapy (absence of response after 8 days)
- patient consent and/or parent consent
- less of 10 kgs BW
- clinical or biological state precluding the apheresis
- previous GVHD therapy with anti-lymphocyte serum (excepted in the conditioning
regimen)