Informations générales (source: ClinicalTrials.gov)
Study Aiming at Researching Diagnostic Markers for the Recognition of Precancerous States, Tracking, Follow-up, and the Identification of New Therapeutic Targets for Mesothelioma in Patients With Atypical Mesothelial Hyperplasia.
Observational
University Hospital, Caen (Voir sur ClinicalTrials)
avril 2007
29 juin 2024
RATIONALE: Studying levels of mesothelin and osteopontin in samples of blood from
patients with mesothelioma or atypical mesothelial hyperplasia may help doctors identify
biomarkers related to cancer.
PURPOSE: This research study is looking at mesothelin and osteopontin as diagnostic
markers in patients with mesothelioma or atypical hyperplasia.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU de Caen - 14033 - Caen - France | Francoise Galateau-Salle | Contact (sur clinicalTrials) | |||
Critères
Tous
DISEASE CHARACTERISTICS:
Inclusion criteria:
- Diagnosis of mesothelial hyperplasia and meeting 1 of the following criteria:
- Confirmed prior exposure to asbestos and presence of pleural effusion and meets
1 of the following diagnostic criteria:
- Mesothelioma
- Mesothelial hyperplasia of unspecified malignancy
- Reactional inflammatory hyperplasia
- No asbestos exposure but pleural effusion with pleural malignant mesothelioma
or pulmonary metastasis
- Prior exposure to asbestos, no pleural effusion, and asymptomatic (pleural
plaques present)
- No prior exposure to asbestos but with benign pleural effusion
- Tissue obtained by pleuroscopy, surgical biopsy, or video-thoracoscopy available
- Paraffin-embedded and frozen tissue available
Exclusion criteria:
- Solitary fibrous tumor
- Diffuse pleural fibrosis
- Purulent pleurisy
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- No prior chemotherapy or radiotherapy
Inclusion criteria:
- Diagnosis of mesothelial hyperplasia and meeting 1 of the following criteria:
- Confirmed prior exposure to asbestos and presence of pleural effusion and meets
1 of the following diagnostic criteria:
- Mesothelioma
- Mesothelial hyperplasia of unspecified malignancy
- Reactional inflammatory hyperplasia
- No asbestos exposure but pleural effusion with pleural malignant mesothelioma
or pulmonary metastasis
- Prior exposure to asbestos, no pleural effusion, and asymptomatic (pleural
plaques present)
- No prior exposure to asbestos but with benign pleural effusion
- Tissue obtained by pleuroscopy, surgical biopsy, or video-thoracoscopy available
- Paraffin-embedded and frozen tissue available
Exclusion criteria:
- Solitary fibrous tumor
- Diffuse pleural fibrosis
- Purulent pleurisy
PATIENT CHARACTERISTICS:
- Not specified
PRIOR CONCURRENT THERAPY:
- No prior chemotherapy or radiotherapy