Informations générales (source: ClinicalTrials.gov)
Nutritional Status of Patients Victims of Haemorragic Accidents With Antivitamins K
Observational
University Hospital, Clermont-Ferrand (Voir sur ClinicalTrials)
août 2012
janvier 2014
29 juin 2024
Bleeding under vitamin K antagonists are a major iatrogenic causes of hospitalization,
subject to a fatal outcome in more than one third of cases, mortality is particularly
high in cases of serious bleeding, including intracerebral hemorrhage. If the INR
measured in these patients are often away from the higher value of the target range, a
significant proportion of bleeding were observed for INR between 2 and 3. The study
captures the components of the nutritional status of patients on oral anticoagulants,
including any micronutrient deficiencies, to determine whether nutritional status is an
independent risk factor for bleeding
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU Clermont-Ferrand - 63003 - Clermont-Ferrand - France | Patrick LACARIN | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Patients, male or female, aged over 18, under oral anticoagulant therapy with
antivitamins K.
- INR greater than 1.5, in the therapeutic range or overdose
- Patient have read, understood and signed the consent form or inclusion emergency
consent of the person with confidence
- Case-control study: patients under oral anticoagulant with severe hemorrhagic
accident compared with patients without hemorrhagic accident. Cases will be matched
to controls based on age, sex, and the value of INR :
Case:
Patients victims of serious hemorrhagic accident on VKAs, supported emergency Adults.
Will be considered severe hemorrhagic stroke, accidents requiring the use of a reversion
by PPSB (Kaskadil ®)
Control :
Patients on VKAs supported the Emergency Adults for a reason other than bleeding.
- Patients, male or female, aged over 18, under oral anticoagulant therapy with
antivitamins K.
- INR greater than 1.5, in the therapeutic range or overdose
- Patient have read, understood and signed the consent form or inclusion emergency
consent of the person with confidence
- Case-control study: patients under oral anticoagulant with severe hemorrhagic
accident compared with patients without hemorrhagic accident. Cases will be matched
to controls based on age, sex, and the value of INR :
Case:
Patients victims of serious hemorrhagic accident on VKAs, supported emergency Adults.
Will be considered severe hemorrhagic stroke, accidents requiring the use of a reversion
by PPSB (Kaskadil ®)
Control :
Patients on VKAs supported the Emergency Adults for a reason other than bleeding.
- underage patients
- Patients who have not read or understood nor signed the consent form or refusal of
the reference person.
- pregnant women
- Patients with a pacemaker and / or implantable defibrillator
- Patients with mechanical valve