Informations générales (source: ClinicalTrials.gov)
Comparison Between Epinephrine and Exercise Test in QT Long Syndrome Patients With KCNQ1 or KCNH2 Mutation Without Long QT Interval in Rest ECG (QT long)
Interventional
N/A
Nantes University Hospital (Voir sur ClinicalTrials)
mai 2012
mai 2018
29 juin 2024
The aim of the study is to evaluate the best stress exam to unmask long QT in patient
with KCNQ1 or KCNH2 mutation without long QT interval in rest electrocardiogram.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU Toulouse - 31059 - Toulouse - France | Philippe MAURY, PH | Contact (sur clinicalTrials) | |||
| CHU Tours - 37170 - Tours - France | BABUTY Dominique, PU-PH | Contact (sur clinicalTrials) | |||
| Nantes Universitary Hospital - 44093 - Nantes - France | Contact (sur clinicalTrials) | ||||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Bordeaux Universitary Hospital - 33604 - Bordeaux - France | Frederic SACHER, PH | Contact (sur clinicalTrials) | |||
| CHU Montpellier - 34295 - Montpellier - France | Jean-Luc PASQUIE, PH | Contact (sur clinicalTrials) | |||
| CHU Rouen - 76031 - Rouen - France | Frederic ANSELME, PH | Contact (sur clinicalTrials) | |||
| Marseille Universitary Hospital - 13385 - Marseille - France | Jean-Claude DEHARO, PU-PH | Contact (sur clinicalTrials) | |||
| Rennes Universitary Hospital - 35033 - Rennes - France | Philippe MABO, PU-PH | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
Patients with QTc<470 msec, and with molecular analysis (KCNQ1 or KCNH2 genes) performed
in order to include 65 patients with KCNQ1 or KCNH2 mutation and 65 patients without
KCNQ1 or KCNH2 mutation (controls).
Patients with QTc<470 msec, and with molecular analysis (KCNQ1 or KCNH2 genes) performed
in order to include 65 patients with KCNQ1 or KCNH2 mutation and 65 patients without
KCNQ1 or KCNH2 mutation (controls).
- QTc interval >470msec
- Treatment interfering with cardiac repolarisation
- Under 15 years old
- Pregnant women
- Contraindication to exercise or epinephrine tests
- Patients without social coverage