Informations générales (source: ClinicalTrials.gov)
Outcome of Acquired Haemophilia With Steroid Combined With Cyclophosphamide Versus Steroid Combined With Rituximab (CREHA Study) (CREHA)
Interventional
Phase 3
University Hospital, Rouen (Voir sur ClinicalTrials)
mai 2012
juin 2020
29 juin 2024
CREHA project is a study comparing steroid combined with cyclophosphamide versus steroid
combined with rituximab in patients with acquired haemophilia. The study will test the
hypothesis that steroid combined with cyclophosphamide is more effective than steroid
plus rituximab for FVIII inhibitor eradication in acquired haemophilia.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Bicêtre | Olivier LAMBOTTE, MD, PhD | Contact (sur clinicalTrials) | |||
| AP-HP - Hôpital Cochin | Philippe BLANCHE, MD | Contact (sur clinicalTrials) | |||
| AP-HP - Hôpital Europeen Georges Pompidou | Jacques POUCHOT, MD, PhD | Contact (sur clinicalTrials) | |||
| AP-HP - Hôpital Henri Mondor-Albert Chenevier | Marc MICHEL, MD, PhD | Contact (sur clinicalTrials) | |||
| AP-HP - Hôpital Jean Verdier | Olivier FAIN, MD, PhD | Contact (sur clinicalTrials) | |||
| EFS IDF SITE BICHAT | Thomas PAPO, MD, PhD | Contact (sur clinicalTrials) | |||
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| AP-HM, University Hospital La Conception - 13385 - Marseille - France | Nicolas SCHLEINITZ, MD, PhD | Contact (sur clinicalTrials) | |||
| Hopsital Bretonneau - 37044 - Tours - France | François MAILLOT, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital Archet 1 - 06202 - Nice - France | Pierre-Yves JEANDEL, MD | Contact (sur clinicalTrials) | |||
| Hospital Lyon Sud - 69495 - Pierre-Benite - France | Isabelle DURIEU, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital Nord - 42055 - Saint-Etienne - France | Pascal CATHEBRAS, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital Purpan - 31059 - Toulouse - France | Laurent SAILLER, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital Amiens - 80054 - Amiens - France | Jean SCHMIDT, MD | Contact (sur clinicalTrials) | |||
| University Hospital Bocage - 21079 - Dijon - France | Bernard BONNOTTE, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital Côte de Nacre - 14033 - Caen - France | Boris BIENVENU, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital Michallon - 38043 - Grenoble - France | Laurence BOUILLET, MD | Contact (sur clinicalTrials) | |||
| university Hospital of Limoges - 87042 - Limoges - France | Elizabeth VIDAL-CATHALA, MD,PhD | Contact (sur clinicalTrials) | |||
| University Hospital of Nantes, Hospital Hôtel-Dieu - 44093 - Nantes - France | Mohamed HAMIDOU, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital of Poitiers - 86021 - Poitiers - France | Pascal ROBLOT, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital of Rouen - 76031 - Rouen - France | Hervé LEVESQUE, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital Saint-Eloi - 34295 - Montpellier - France | Alain LE QUELLEC, MD, PhD | Contact (sur clinicalTrials) | |||
| University Regional Hospital Hautepierre - 67098 - Strasbourg - France | Anne BOUGARIT, MD, PhD | Contact (sur clinicalTrials) | |||
| University Regional Hospital of Lille - 59037 - Lille - France | Marc LAMBERT, MD | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Hospital Ambroise Paré - 92104 - Boulogne-Billancourt - France | Thomas HANSLIK, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital of Béziers - 34525 - Béziers - France | Eric OZIOL, MD | Contact (sur clinicalTrials) | |||
| Hospital Pitié-Salpêtrière - 75651 - Paris 13e - France | Zahir AMOURA, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital Rangueil - 31059 - Toulouse - France | Dominique CHAUVEAU, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital Saint-Louis - 75475 - Paris 10e - France | Dominique FARGE-BANCEL, MD, PhD | Contact (sur clinicalTrials) | |||
| Hospital Sud / Hospital Pontchaillou - 35000 - Rennes - France | Patrick JEGO, MD, PhD | Contact (sur clinicalTrials) | |||
| Regional Center of Haemophilia Treatment (CRTH) de Lorraine - Nancy - France | Brigit FROTSCHER, MD | Contact (sur clinicalTrials) | |||
| University Hospital G. Montpied - 63003 - Clermont-Ferrand - France | Marc ANDRE, MD,PhD | Contact (sur clinicalTrials) | |||
| University Hospital of Bordeaux - Hospital Haut-Lévêque - 33604 - Pessac - France | Jean-François VIALLARD, MD, PhD | Contact (sur clinicalTrials) | |||
| University Hospital of Brest - Hospital La cavale Blanche - 29609 - Brest - France | Aurélien DELLUC, MD | Contact (sur clinicalTrials) | |||
| University Hospital of Dijon - Hospital Général - 21033 - Dijon - France | Jean-François BESANCENOT, MD, PhD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- men or women
- women post-menpausal or with ongoing contraception
- 18 years old or more
- diagnosis of acquired hemophilia
- patient must be insured
- patient has provided written informed consent prior to enrolment
- patient compliant
- men or women
- women post-menpausal or with ongoing contraception
- 18 years old or more
- diagnosis of acquired hemophilia
- patient must be insured
- patient has provided written informed consent prior to enrolment
- patient compliant
- constitutional hemophilia
- chemotherapy
- ongoing treatment with prednisone > 20mg further more 1 month
- ongoing treatment with prednisone >0.7 mg/d further more 10 days
- thrombocytopenia
- leukopenia
- chronic disease