Informations générales (source: ClinicalTrials.gov)
Anatomical Clinical Correlations. Neuropsychological and Brain Medical Imaging Study in Brain Damaged Subjects. (CORAC)
Interventional
N/A
University Hospital, Rouen (Voir sur ClinicalTrials)
mai 2013
janvier 2019
29 juin 2024
Two groups of subjects will be constitute: (i) patients with circumscribed brain injury
(including stroke, vascular malformations, tumor or circumscribed infectious lesions) or
degenerative disorders and selective cognitive disorders; (ii) healthy control subjects.
The objective of this project is to evaluate specific neuropsychological deficits and
apply current brain imaging techniques (anatomical, diffusion, functional) to patients
suffering from these cognitive deficits due to brain damage, in order to elucidate the
brain mechanisms underlying these deficits.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU - Hôpitaux de Rouen - 76031 - Rouen - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
Inclusion Criteria:
- age between 18 and 80 years
- french language
- effective contraception for women during the study
- informed consent
- no alcohol intake the day before the exam
- for patients only, focal cerebral lesion (stroke, malformation, tumor, inflammatory,
infectious, traumatic), neonatal pathology or degenerative disease with cognitive
deficit
- age between 18 and 80 years
- french language
- effective contraception for women during the study
- informed consent
- no alcohol intake the day before the exam
- for patients only, focal cerebral lesion (stroke, malformation, tumor, inflammatory,
infectious, traumatic), neonatal pathology or degenerative disease with cognitive
deficit
- for healthy volunteers: previous neurological history (except non complicated
migraine), previous psychiatric history (except depression with good evolution or
anxiety with maximum one anxiolytic treatment), or severe cranial traumatism
- for patients: vigilance disorders, severe depression or anxiety.
- for both: psychotropic medication other than a hypnotic or an anxiolytic at low
doses without dose modification for at least one month, severe visual or auditory
impairment, patient without judicial or administrative liberty, measure of legal
protection or no capable to express their consent, pregnancy or breastfeeding,
contraindication for MRI, participation in another trial or former involvement in
another trial within one month