Detail Article

Informations générales (source: ClinicalTrials.gov)

Numéro NCT

NCT02006797 Statut inconnu

Titre

Impact of Drug Reconciliation at Discharge and Pharmaceutical Communication Between Hospital and Community Pharmacists on Drug Related Problems: Study Protocol for a Cluster Randomized Cross-over Trial

Type

Interventional

Pathologie

Phase

N/A

Promoteur

University Hospital, Tours (Voir sur ClinicalTrials)

Date de début

janvier 2014

Date de fin

décembre 2015

Dernière mise à jour

17 septembre 2025

Résumé

This study will evaluate the impact of a communication between hospital pharmacist and community pharmacists in addition to drugs reconciliation procedure at discharge. It will be conducted in 21 french public hospitals.

Détail

Voir le détail Transition points during hospitalization are at risk of drug related problems (DRP) especially admission and discharge. Reconciliation procedure at admission lead by a clinical pharmacist had been proved to decrease DRP. The community pharmacist (CP) is often the first health professional that patients meet at discharge. He/she is in charge of dispensing their medication to patients and give treatment information. However because of lack of information community pharmacist is not always able to identify problems and this may lead to dispense wrong drugs and/or wrong dosage and/or give wrong information. The objective of this study is to assess the impact of drug reconciliation performed at discharge completed by a communication between the Hospital Pharmacist (HP) and community pharmacist on drug related problem during the 7 days following discharge at home. The study is a cluster randomized cross-over trial. It involves 21 French universitarian and non-universitarian hospitals with 42 care units: 22 medical units and 20 surgical units. Each unit (a unit corresponds to a cluster) is involved during two consecutive 14-day periods which are randomly assigned as "experimental" or "control" where control corresponds to usual care. During the experimental period, for each eligible patient discharged during the period, a reconciliation procedure will be performed by the HP, with communication to the patient. The HP will further inform the patient's community pharmacist about patient's drug therapy [modification in home medication, acute drugs prescribed, shelved treatments and/or labs results to survey patient]. Eligible patients will be over 18, attending to the same community pharmacist for at least 3 months. We will exclude patients with a length stay over 21 days (too many therapeutic modifications), those who do not return to home, and also palliative patient. The primary outcome is a composite outcome associating any kind of drug misuse during the 7 days following discharge. It will be assessed by phone at day 7 (+/-2) by a pharmacist in charge of the study (PCS) will phone both patients and community pharmacists . The secondary outcome will be the unplanned hospitalizations observed in each group assessed by phone at day 35 (+/-5). We plan to recruit 1,176 patients, i.e. 14 per period per unit. This study will assess the impact of a reconciliation procedure at discharge followed by a communication between HP and community pharmacists . Also it will identify the type of patients for which the intervention is the most relevant in France and may be generalized to other countries that have the same care organisation. Fermer le détail

Etablissements

Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
Centre Hospitalier - 41000 - Blois - France	Mathilde EMONET	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier - 62408 - Bethune - France	Catherine FLORET	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Alès-Cévennes - 30100 - Ales - France	Vincent BOUIX	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Compiègne-Noyon - 60200 - Compiegne - France	Anne-Marie LIEBBE	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Universitaire - 31000 - Toulouse - France	Cécile LEBAUDY	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Universitaire - 37000 - Tours - France	Xavier POURRAT	En recrutement	Contact (sur clinicalTrials)
Centre Hospitalier Universitaire - 86000 - Poitiers - France	Sophie SURY-LESTAGE	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital Archet - 06000 - Nice - France	Rémy COLLOMP	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital de Hautepierre - 67000 - Strasbourg - France	Bénédicte GOURIEUX	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital de la Cavale Blanche - 29200 - Brest - France	Maud PERENNES	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital de Mercy Metz-Thionville - 57085 - Metz - France	Grégory RONDELOT	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital ESTAING - 63000 - Clermont-ferrand - France	Anne BOYER	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital Inter Armées - 94160 - Saint Mande - France	Virginie LAMAND	Recrutement non commencé	Contact (sur clinicalTrials)
Hopital Jacques Monod - 76290 - Le Havre - France	Dorothée LAURE-OLIVIER	Recrutement non commencé	Contact (sur clinicalTrials)
Hopitaux civils de Colmar - 68000 - Colmar - France	Christelle LEMARIGNIER	Recrutement non commencé	Contact (sur clinicalTrials)
Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
Centre Hospitalier - 30000 - Nimes - France	Clarisse ROUX	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier - 72000 - Le Mans - France	Anne-marie CAMINONDO	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Pierre Bérégovoy - 58000 - Nevers - France	Marie-Odette TISSERON-GUYOT	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Universitaire - 38000 - Grenoble - France	Pierrick BEDOUCH	Recrutement non commencé	Contact (sur clinicalTrials)
Centre Hospitalier Universitaire - 49000 - Angers - France	Frédéric MOAL	Recrutement non commencé	Contact (sur clinicalTrials)
CHU Conception - 13000 - Marseille - France	Philippe MONGES	Recrutement non commencé	Contact (sur clinicalTrials)

Critères

Genre

Tous

Nombre d'inclusion

Critère d'inclusion

Inclusion Criteria:

- patients over 18

- patients attending to the same CP for at least 3 months

- patients speaking french

Critère de non inclusion

- patients with a length stay over 21 days (too many therapeutic modifications),

- patients who do not return to home,

- palliative patients and/or expected end of life

- patients that will not give their informed consent

NCT02006797 - Impact of Drug Reconciliation at Discharge and Pharmaceutical Communication Between Hospital and Community Pharmacists on Drug Related Problems: Study Protocol for a Cluster Randomized Cross-over Trial

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