Informations générales (source: ClinicalTrials.gov)
Effect of the Continuous Positive Airway Pressure on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension (POP-ART)
Observational
University Hospital, Grenoble (Voir sur ClinicalTrials)
septembre 2015
février 2017
29 juin 2024
Resistant hypertension is defined as uncontrolled blood pressure (BP ≥ 140/90mmHg)
despite the current use of three or more antihypertensive drugs at full doses, including
a diuretic. Obstructive Sleep Apnea (OSA) is at high risk for cardiovascular morbidity
and is highly prevalent in patients with resistant hypertension.
The prospective observational POP-ART study will assess the efficacy of continuous
positive airway pressure (CPAP) treatment on BP in patients with resistant hypertension
and collect data from usual care.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Clinique des Eaux Claires, Groupe Hospitalier Mutualiste - 38000 - Grenoble - France | Jean-Philippe Baguet, MD, PhD | Contact (sur clinicalTrials) | |||
| Clinique du Tondu - 33000 - Bordeaux - France | Olivier Coste, MD | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Bordeaux University Hospital - 33075 - Bordeaux - France | Philippe Gosse, Md, PhD | Contact (sur clinicalTrials) | |||
| Grenoble University Hospital - 38700 - Grenoble - France | Gilles Barone-Rochette, MD, PhD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Patient with resistant hypertension uncontrolled by 3 or more antihypertensive
agents
- Patient with severe OSA (apnea-hypopnea index > 30 or > or equal to 15 with
excessive daytime sleepiness), or with mild to moderate OSA without excessive
daytime sleepiness, or without OSA.
- Ambulatory patient
- Patient with resistant hypertension uncontrolled by 3 or more antihypertensive
agents
- Patient with severe OSA (apnea-hypopnea index > 30 or > or equal to 15 with
excessive daytime sleepiness), or with mild to moderate OSA without excessive
daytime sleepiness, or without OSA.
- Ambulatory patient
- Body mass index ≥40 kg/m2
- Other identifiable causes of hypertension
- Contraindication to CPAP treatment or patient already treated with CPAP