Informations générales (source: ClinicalTrials.gov)
COMET Study Effectiveness of a Cognitive Remediation Program of Memory in Patients With Temporal Lobe Epilepsy (COMETE)
Interventional
N/A
Central Hospital, Nancy, France (Voir sur ClinicalTrials)
mars 2016
janvier 2021
29 juin 2024
Studies on the cognitive function have highlighted promising results concerning
attention. In contrast, in the field of memory, the single cohort study that has been
carried out, has not been randomised, with non comparable groups, the significant
outcomes are therefore to be balanced.
In this study, patients with focal and structural temporal lobe epilepsy will be
randomised in 2 groups : the COMETE group where patients will attend a specific
rehabilitation programme of memory and the control group where patients will benefit from
a standard treatment.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Service de Neurologie, Hôpital Central, CHRU de Nancy - 54 035 - Nancy - Lorraine - France | Helene BRISSART, Dr | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Adults with structural temporal lobe epilepsy, according to Fischer et al (2005)
criteria.
- Patients aged 18-70
- Patients with epilepsy for more than 2 year
- Patients with mild to severe memory impairment (minimum score : -1,6σ / average at
Buschke Reminding Test, learning index
- Patients with equal or higher Intellectual Quotient than 70 (WAIS-IV)
- stabilized anti epileptic treatment (same treatment for the last 6 months)
- Patient who has given informed consent in writing
- Patients with social insurance
- Patients with internet connexion for weekly training at home
- Adults with structural temporal lobe epilepsy, according to Fischer et al (2005)
criteria.
- Patients aged 18-70
- Patients with epilepsy for more than 2 year
- Patients with mild to severe memory impairment (minimum score : -1,6σ / average at
Buschke Reminding Test, learning index
- Patients with equal or higher Intellectual Quotient than 70 (WAIS-IV)
- stabilized anti epileptic treatment (same treatment for the last 6 months)
- Patient who has given informed consent in writing
- Patients with social insurance
- Patients with internet connexion for weekly training at home
- other progressive associated neurological (history of stroke for example) or
psychiatric disease
- temporal lobe surgery within following 12 months
- presence of a progressive brain lesion
- legally protected adults or adults incapable of giving informed consent
- persons who are deprived of their liberty by judicial or administrative decision