Informations générales (source: ClinicalTrials.gov)
Is There a Change in the Total Metabolism Over 24 Hours for Narcoleptic Children That Could Explain Their Tendency to Obesity? (Narcolepsy)
Interventional
N/A
Hospices Civils de Lyon (Voir sur ClinicalTrials)
décembre 2013
novembre 2019
29 juin 2024
A significant weight gain and obesity are observed for most patients with narcolepsy,
mainly at the beginning of the disease and narcolepsy in young children. There is no
specific study on the population and the consequences of overweight in the lives of these
long-term patients. Narcoleptic patients gain weight significantly at the onset of their
illness. It is also known that weight gain is not related to the treatment of narcolepsy.
The etiology of obesity in narcoleptic patients is not established. Several assumptions
were made (physical activity, leptin diet, metabolism). The reason and the
pathophysiology of overweight and obesity in this population therefore remain unclear.
In this study, potential change in the total metabolism (24h) for narcoleptic children
that could explain their tendency to obesity will be assessed ?
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Service d'Exploration et pathologie du sommeil, Hôpital Femme Mère Enfant - 69677 - Bron - France | Patricia Franco, MD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
NARCOLEPTIC PATIENTS
- Girl or boy age> 6 years <18 years;
- Narcoleptic: defined by the ICSD diagnostic criteria 2 (International Classification
of Sleep Disorders)
- Beginning of the troubles there more than 6 months
- Parental consent and agreement of the child.
HYPERSOMNIC PATIENTS
- Girl or boy age> 6 years <18 years;
- Hypersomnic : defined by the ICSD diagnostic criteria 2 (International
Classification of Sleep Disorders)
- Beginning of the troubles there more than 6 months
- Parental consent and agreement of the child.
NARCOLEPTIC PATIENTS
- Girl or boy age> 6 years <18 years;
- Narcoleptic: defined by the ICSD diagnostic criteria 2 (International Classification
of Sleep Disorders)
- Beginning of the troubles there more than 6 months
- Parental consent and agreement of the child.
HYPERSOMNIC PATIENTS
- Girl or boy age> 6 years <18 years;
- Hypersomnic : defined by the ICSD diagnostic criteria 2 (International
Classification of Sleep Disorders)
- Beginning of the troubles there more than 6 months
- Parental consent and agreement of the child.
NARCOLEPTIC PATIENTS
- Secondary Narcolepsy;
- Narcolepsy already treated with psychostimulant or anticataplectic;
- Restless legs;
- Sleep apnea syndrome;
- Obesity known outside narcolepsy cause;
- Absence of parental consent.
HYPERSOMNIC PATIENTS
- symptomatic or secondary hypersomnia;
- Hypersomnia already treated psychostimulant or anticataplectic; Restless legs;
- Sleep apnea syndrome;
- Pathology neurological, psychiatric, endocrine or concurrent;
- Lack of parental consent