Informations générales (source: ClinicalTrials.gov)

NCT02891356 Statut inconnu
Bone Mass Changes in Anorexia Nervosa Patient Followed During 4 Years and Relationship Between Bone Loss and Adipokines. (AMOS)
Observational
  • Anorexie
  • Anorexie mentale
  • Ostéoporose
University Hospital, Lille (Voir sur ClinicalTrials)
juillet 2013
juillet 2022
29 juin 2024
The mechanism of bone loss in anorexia nervosa is complex. Marrow adipose tissue seems to play a role in the regulation of bone metabolism. Adipocytes secrete cytokines and adipokines that either stimulate or inhibit adjacent osteoblasts. This study consist to explore the relationship in anorexia nervosa patients with change in bone mineral density and adipokines like leptin, adiponectin and Préf-1 Bone mineral densities will be measure in 180 anorexia nervosa patients at inclusion and every two years during 6 years.It is assessed blood and urinary calcium and phosphate levels, bone remodelling markers and adipokines (leptin, adiponectin and Préf-1)
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Etablissements

Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
Hôpital Roger Salengro, CHRU de Lille - Lille - France En recrutement Contact (sur clinicalTrials)

Critères

Femme
Inclusion Criteria:

- anorexia patient defined by DSM IV diagnostic criteria


- patient with other psychiatric disease

- patient with other a metabolic bone disease