Informations générales (source: ClinicalTrials.gov)
Assessment of White Blood Cell SPECT/CT in Monitoring Antibiotic Treatment in Patients With Diabetic Foot Osteomyelitis
Observational
Hospices Civils de Lyon (Voir sur ClinicalTrials)
janvier 2014
décembre 2016
29 juin 2024
Osteomyelitis is a risk factor for lower extremity amputation in diabetic people.
Antibiotic therapy allows a remission in 60 to 80% of cases. However the optimal duration
of antibiotic therapy remains controversy due to the absence of validated marker of
osteomyelitis remission. We have previously shown that the negativity of white blood cell
SPECT/CT (Single Photon Emission Computed Tomography/Computed Tomography) imaging at the
end of treatment allowed to predict remission of osteomyelitis at 1 year in all cases. A
positive imaging was associated with recurrence in 70% of cases. The aim of our study was
to evaluate prospectively the interest of white blood cell SPECT/CT to set the duration
of antibiotic therapy.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Service d'Endocrinologie-Diabétologie-Maladies de la nutrition, GH Sud, Hospices Civils de Lyon - 69495 - Pierre-Bénite - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
Inclusion Criteria:
- Age >18 years
- Diabetes
- Osteomyelitis defined by soft tissue infection and/or positive probe-to-bone test
and suggestive signs of osteomyelitis on plain-X-Ray
- Age >18 years
- Diabetes
- Osteomyelitis defined by soft tissue infection and/or positive probe-to-bone test
and suggestive signs of osteomyelitis on plain-X-Ray
- Indication for acute surgical bone resection or amputation