Informations générales (source: ClinicalTrials.gov)
Analysis of the Capacity to Regulate Physical Efforts and to Estimate Its Intensity as an Endophenotype of Anorexia Nervosa, Because of a Specific Impact of the Physical Effort at the Emotional, Cognitive, Pain, Genetic and Biological Level (CAPANOX)
Interventional
N/A
Centre Hospitalier St Anne (Voir sur ClinicalTrials)
février 2017
septembre 2020
29 juin 2024
The purpose of this study is to check if patients, but also relatives (as they share
familial and genetic risk factors), are having more difficulties in regulating a
spontaneous, pleasant physical effort (doing "too much") compared to healthy controls,
and if physical efforts are participating to core symptoms of anorexia nervosa, such as
more appetite (instead of less), less pain, more abnormal body image, and less cognitive
flexibility.
Such a result could help to further understand the role of difficulties with physical
exercise as part of the phenotype of anorexia nervosa.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| GHU PARIS PSY ET NEUROSCIENCES | Philip GORWOOD, MD., PhD | Contact (sur clinicalTrials) | |||
Critères
Femme
Inclusion Criteria:
Patients :
- Woman
- 18 - 50 years
- eating disorders (with or without bulimia) according to the EDI-2 (Eating Disorder
Inventory) and the MINI (Mini International Neuropsychiatric Interview)
- BMI (Body Mass index) between 14 and 17,5
- first degree relative without ED (eating disorders)
First degree relatives :
- Woman
- 18 - 50 years
- Mother or sister of patient with eating disorders
- BMI (Body Mass index) upper to 17,5
- Healthy of all ED (eating disorders)
Controls :
- Woman
- 18 - 50 years
- BMI > 17,5
- Without ED (eating disorders)
Patients :
- Woman
- 18 - 50 years
- eating disorders (with or without bulimia) according to the EDI-2 (Eating Disorder
Inventory) and the MINI (Mini International Neuropsychiatric Interview)
- BMI (Body Mass index) between 14 and 17,5
- first degree relative without ED (eating disorders)
First degree relatives :
- Woman
- 18 - 50 years
- Mother or sister of patient with eating disorders
- BMI (Body Mass index) upper to 17,5
- Healthy of all ED (eating disorders)
Controls :
- Woman
- 18 - 50 years
- BMI > 17,5
- Without ED (eating disorders)
All groups :
- Contraindication in the practice of an intensive sport
- Cardiovascular Family history with risk of cardiovascular unwanted events
- Cardiovascular, surgical personal Histories, ostéoarticulaires or musculo-tendinous
against indicating to the practice of a sport
- Intercurrents psychiatric pathologies (humor or psychotics disorders, chronic or
acute)
Related and controls :
Diagnosis of ED (eating disorders) in the EDI-2 and in the MINI