Informations générales (source: ClinicalTrials.gov)
Is Caffeine an Environmental Modifier in Huntington's Disease? (CrEAM-HD)
Observational
University Hospital, Lille (Voir sur ClinicalTrials)
octobre 2017
octobre 2023
04 janvier 2025
The aim of the study is to establish if caffeine consumption is associated with the
evolution of the disease in premanifest HD.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Henri Mondor-Albert Chenevier | Contact (sur clinicalTrials) | ||||
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| CHU de Amiens - Amiens - France | Contact (sur clinicalTrials) | ||||
| CHU de Angers - Angers - France | Contact (sur clinicalTrials) | ||||
| CHU de Nancy - Nancy - France | Contact (sur clinicalTrials) | ||||
| Hôpital Roger Salengro, CHRU - Lille - France | Contact (sur clinicalTrials) | ||||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| AH-HP La Pitié-Salpétrière - 75679 - Paris 14 - France | Contact (sur clinicalTrials) | ||||
| CHU de Grenoble - Grenoble - France | Contact (sur clinicalTrials) | ||||
| CHU Montpellier - Montpellier - France | Contact (sur clinicalTrials) | ||||
| CHU Pellegrin - Bordeaux - France | Contact (sur clinicalTrials) | ||||
| CHU Purpan - Toulouse - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
Inclusion Criteria:
- HD mutation carriers (>36 CAG)
- premanifest (total motor UHDRS < 5)
- estimated time to diagnosis between 3 and 10 years
- adults older than 21 years (in order to exclude juvenile patients who begin the
disease before 21 years)
- informed consent signed
- with a social protection
- HD mutation carriers (>36 CAG)
- premanifest (total motor UHDRS < 5)
- estimated time to diagnosis between 3 and 10 years
- adults older than 21 years (in order to exclude juvenile patients who begin the
disease before 21 years)
- informed consent signed
- with a social protection
- MRI contraindication
- pregnant and lactating women
- People under guardianship, trusteeship, deprive of freedom