Informations générales (source: ClinicalTrials.gov)
Intra-nodal Injection of Gentamicin for the Treatment of Suppurated Cat Scratch Disease's Lymphadenitis: A Randomized Controlled Study (BIGG)
Interventional
Phase 3
University Hospital, Toulouse (Voir sur ClinicalTrials)
mai 2017
décembre 2025
28 août 2024
To compare effect of intra-nodal injection of gentamicin versus placebo on the outcome at
28 days of suppurated cat scratch disease's (CSD) lymphadenitis treated by oral
azithromycin.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Amiens-Picardie Hospital - Amiens - France | Jean-Luc SCHMIT, MD | Contact (sur clinicalTrials) | |||
| Angers Hospital - Angers - France | Vincent DUBEE, MD | Contact (sur clinicalTrials) | |||
| Auch Hospital - Auch - France | Sophie ARISTA, MD | Contact (sur clinicalTrials) | |||
| Castres Hospital - Castres - France | Florence-Sarah KHATIBI, MD | Contact (sur clinicalTrials) | |||
| Hospices Civils Lyon - Lyon - France | Florence ADER, MD | Contact (sur clinicalTrials) | |||
| Limoges University Hospital - Limoges - France | Pierre WEINBRECK, MD | Contact (sur clinicalTrials) | |||
| Montpellier University Hospital - Montpellier - France | David MORQUIN, MD | Contact (sur clinicalTrials) | |||
| Perpignan Hospital - Perpignan - France | Léa COLOMBAIN, MD | Contact (sur clinicalTrials) | |||
| Saint-Brieuc Hospital - Saint-Brieuc - France | Rodolphe BUZELE, MD | Contact (sur clinicalTrials) | |||
| Saint-Nazaire Hospital - Saint-Nazaire - France | Julia BROCHARD, MD | Contact (sur clinicalTrials) | |||
| Tarbes Hospital - Tarbes - France | Florian BUSATO, MD | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Albi Hospital - Albi - France | Marie-Anne LAFFONT, MD | Contact (sur clinicalTrials) | |||
| Bordeaux University Hospital - Bordeaux - France | Michel DUPON, MD | Contact (sur clinicalTrials) | |||
| Cahors Hospital - Cahors - France | Stéphane SIRE, MD | Contact (sur clinicalTrials) | |||
| Microbiology Laboratory - 31059 - Toulouse - France | Guillaume MARTIN-BLONDEL, MD | Contact (sur clinicalTrials) | |||
| Montauban Hospital - Montauban - France | Marc DELAVAISSIERE, MD | Contact (sur clinicalTrials) | |||
| Nîmes University Hospital - Nîmes - France | Catherine LECHICHE, MD | Contact (sur clinicalTrials) | |||
| Pau Hospital - Pau - France | Valérie GABORIEAU, MD | Contact (sur clinicalTrials) | |||
| Rennes Hospital - Rennes - France | Matthieu REVEST, MD | Contact (sur clinicalTrials) | |||
| Rodez Hospital - Rodez - France | Bruno GUERIN, MD | Contact (sur clinicalTrials) | |||
| Vendée Hospital - La Roche-sur-Yon - France | Thomas GUIMARD, MD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Informed consent
- Suppurated CSD's adenitis:
- Suppurated form of adenitis confirmed by echography
- Serology positive for Immunoglobulin G and/or Immunoglobulin M against B.
henselae
- Informed consent
- Suppurated CSD's adenitis:
- Suppurated form of adenitis confirmed by echography
- Serology positive for Immunoglobulin G and/or Immunoglobulin M against B.
henselae
- Suppurated adenitis non related to CSD
- Non-suppurated CSD's adenitis
- Suppurated CSD's adenitis already fistulized
- Suspected visceral B. henselae infection (neurologic or ophthalmic symptoms,
hepato-splenic or valvular involvement confirmed by echography)
- Immunodepression (except diabetes)
- Pregnancy
- Contraindication to pus aspiration from lymphadenitis (history of bleeding or
patient taking curative anticoagulation therapy or platelet count < 50.000/mm3)
- Contraindication to azithromycin (history of QT interval prolongation, history of
liver toxicity of hypersensitivity to macrolides or treatment with ergotamine,
dihydroergotamine, bepridil, cisapride, pimozide, mizolastine or colchicine) or to
aminoglycosides (myasthenia, history of hypersensitivity to aminoglycosides).