Informations générales (source: ClinicalTrials.gov)
Is Variation of Plasmatic Protein Concentration During Continuous Renal Replacement Therapy Predictive of Hypovolemia in Intensive Care Unit?
Observational [Patient Registry]
Hopital Louis Pradel (Voir sur ClinicalTrials)
décembre 2016
décembre 2019
29 juin 2024
The aim of the study is to analyze if blood protein concentration variation during
continuous renal replacement therapy (CRRT) with fluid removal can predict a decrease of
15 % of cardiac index in intensive care unit (ICU) patients. Blood protein concentration,
clinical data describing hemodynamic status (providing data from Pulsion medical system
PiCCO2 ® monitoring), including preload dependency evaluation with passive leg raising,
are collected at different times: before initiation of fluid removal, and after the first
episode of hypotension or one hour after initiation of fluid removal.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Hôpital Cardiologique Louis Pradel - 69350 - Lyon - Rhône Alpes - France | Matthias Jacquet-Lagrèze, M.D., M.Sc. | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Matthias Jacquet-Lagreze - 69000 - Lyon - Rhône - France | Matthias Jacquet-Lagreze, MD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- up to 18 years old
- continuous renal replacement therapy
- Suspicion of fluid overload
- Prescription of fluid removal by the intensivist
- PICCO2 monitoring
- up to 18 years old
- continuous renal replacement therapy
- Suspicion of fluid overload
- Prescription of fluid removal by the intensivist
- PICCO2 monitoring
- pregnancy
- intra abdominal hypertension
- Moribund patient
- Abdominal hypertension