Informations générales (source: ClinicalTrials.gov)
Repetitive Transcranial Magnetic Stimulation as an Analgesic Treatment in Endometriosis Chronic Pain : Feasibility Study (ENDOSTIM)
Interventional
N/A
University Hospital, Clermont-Ferrand (Voir sur ClinicalTrials)
avril 2016
mai 2018
29 juin 2024
Endometriosis is associated with different types of pain (acute, chronic, excess
nociception, neuropathic) generated by different mechanisms in the nervous system. The
rTMS could provide significant analgesia for refractory endometriosis pain.
The aim of the study is to evaluate the feasibility of transcranial magnetic stimulation
(rTMS) for analgesia on chronic refractory endometriosis pain.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU de Clermont-Ferrand - 63003 - Clermont-Ferrand - Auvergne - France | Patrick LACARIN | Contact (sur clinicalTrials) | |||
Critères
Femme
Inclusion Criteria:
- Premenopausal (presence of at least one of the two ovaries and absence of clinical
signs of menopause),
- Not pregnant or breastfeeding;
- At least one painful symptoms related to the existence of endometriosis
(dyspareunia, dysmenorrhea, pain with defecation or urination, neuropathic pain);
- Average VAS> 4/10, at least 4 days out of 7 for at least 3 months;
- Hormonal treatment failure continued in association or not for pain control;
- A level of understanding and satisfying expression in French;
- Monitoring possible during the duration of the study (4 weeks).
- These patients should be affiliated to the French social security and should have
signed a written consent after receiving clear information.
- Premenopausal (presence of at least one of the two ovaries and absence of clinical
signs of menopause),
- Not pregnant or breastfeeding;
- At least one painful symptoms related to the existence of endometriosis
(dyspareunia, dysmenorrhea, pain with defecation or urination, neuropathic pain);
- Average VAS> 4/10, at least 4 days out of 7 for at least 3 months;
- Hormonal treatment failure continued in association or not for pain control;
- A level of understanding and satisfying expression in French;
- Monitoring possible during the duration of the study (4 weeks).
- These patients should be affiliated to the French social security and should have
signed a written consent after receiving clear information.
- Prior treatment with rTMS,
- Industrial accident or notion of litigation
- Cons-indication for rTMS (cortical lesion within 2cm of the motor cortex, ECT
treatment during previous month, epilepsy and / or a history of epilepsy, history of
head trauma, intracranial hypertension;
- Metal clip; pacemaker,
- Pregnant or breastfeeding women;
- Pain lasting less than 3 months;
- Another pain more severe than that associated with endometriosis;
- Lack of filling of the computerized questionnaires on Redcap;
- Incapable of understanding about informed consent,
- Patient under guardianship.