Informations générales (source: ClinicalTrials.gov)
Predictive Value of Aortic Stiffness on Recurrence of Atrial Fibrillation After Disconnection of Pulmonary Veins. (VARIABLE)
Observational
Hospices Civils de Lyon (Voir sur ClinicalTrials)
novembre 2016
mai 2018
29 juin 2024
The ablation of atrial fibrillation (FA) by disconnection of pulmonary veins is a
burgeoning intervention. It allows a long-term treatment of this arrhythmia with a
success rate of about 80%. There are, nevertheless, some recidivism.
Risk factors for recidivism are poorly codified and need further research. Indeed the
identification of factors of poor prognosis could lead to not propose this procedure to
the patients who present them and at least to inform them of an increased risk of
failure.
To date, aortic stiffness has not been studied in the context of assessing the risk
factors for FA recurrence after ablation. On a physiopathological level, the aortic
stiffness leads to increase left ventricle's post-load. Cardiac remodeling was observed
with diastolic dysfunction and increased left atrial size. That may constitute a
substrate for FA recurrence.
In the literature, aortic stiffness can be measured in several ways:
1. Measurement of systolo-diastolic variation of the inner diameter of the aorta by
scanner or transesophageal Echography (ETO).
2. Measuring of the Pulse Wave Velocity.
3. Measurement of aortic calcifications.
The investigators propose to evaluate the impact of aortic stiffness on the recidivism of
FA 6 months after ablation procedure performed in the Croix-Rousse cardiology's
department.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Hospices Civils de Lyon - Hôpital de la Croix Rousse - 69004 - Lyon - France | Pierre Lantelme | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria :
- 18 years old of both sexes,
- Patient carrying a paroxysmal or persistent atrial fibrillation, benefiting from a
first procedure of atrial fibrillation's ablation in the in the Croix-Rousse
cardiology's department.
- Patient who signed the consent to participate in the study.
Exclusion Criteria :
- Patient carrying a permanent atrial fibrillation
- Patient who're in atrial fibrillation during the ablation
- Atrial fibrillation relapse's history after ablation
- Pregnant and nursing women
- Patients refusal.
- 18 years old of both sexes,
- Patient carrying a paroxysmal or persistent atrial fibrillation, benefiting from a
first procedure of atrial fibrillation's ablation in the in the Croix-Rousse
cardiology's department.
- Patient who signed the consent to participate in the study.
Exclusion Criteria :
- Patient carrying a permanent atrial fibrillation
- Patient who're in atrial fibrillation during the ablation
- Atrial fibrillation relapse's history after ablation
- Pregnant and nursing women
- Patients refusal.