Informations générales (source: ClinicalTrials.gov)
COGnitive ImpairmenT in Older HIV-infected Patients ≥ 65 Years Old. (COGITO)
Observational
Fondation Ophtalmologique Adolphe de Rothschild (Voir sur ClinicalTrials)
septembre 2017
septembre 2024
29 juin 2024
Despite combined antiretroviral therapy (cART), milder forms of HIV-associated
neurocognitive disorders (HAND) persist in 20-50% of persons living with HIV (PLHIV).
Since more PLH are at risk for HAND due to aging, the frequency of HAND in PLHIV ≥ 65
years old is important to quantify for planning early intervention to attenuate both
functional and occupational disabilities due to cognitive impairment.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL FONDATION A. DE ROTHSCHILD | Antoine MOULIGNIER | 21/06/2024 13:31:03 | Contacter | ||
Critères
Tous
Inclusion Criteria:
- Personal or familial cognitive complaints
- Individual aged ≥ 65 years old and < 81 years old
- Instrumental activities of daily living (IADL) score between 3-4
- French speaking individual
- Informed consent signed For PLHIV
- HIV infection
- Undetectable HIV viral load ≥ 1 year
- Current cluster of differentiation (CD4) cell count > 100/mm3 For controls
- negative HIV serology ≤ 6 months
- Personal or familial cognitive complaints
- Individual aged ≥ 65 years old and < 81 years old
- Instrumental activities of daily living (IADL) score between 3-4
- French speaking individual
- Informed consent signed For PLHIV
- HIV infection
- Undetectable HIV viral load ≥ 1 year
- Current cluster of differentiation (CD4) cell count > 100/mm3 For controls
- negative HIV serology ≤ 6 months
- Opportunistic infection < 5 years
- Contraindications to MRI