Informations générales (source: ClinicalTrials.gov)
Constitution of a Clinico-radiological Database and a Biobank for Patients With Lacunar Infarcts at Lariboisière Fernand-Widal and Sainte Anne Hospitals
Observational
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
juin 2018
août 2027
11 septembre 2025
The aim of this study is to determine in patients with a recent lacunar strokes (<15
days), the natural history of cognitive disturbances and disability.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| GH PARIS SITE SAINT JOSEPH | JOUVENT Eric | 18/09/2025 17:37:45 | Contacter | ||
| GHU PARIS PSY ET NEUROSCIENCES | JOUVENT Eric | 18/09/2025 17:37:45 | Contacter | ||
| AP-HP Assistance publique - Hôpitaux de Paris | 18/09/2025 17:37:45 | Contacter | |||
| AP-HP - Hôpital Bichat | |||||
| AP-HP - Hôpital Lariboisiere-Fernand Widal | |||||
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| 18/09/2025 17:37:45 | Contact (sur clinicalTrials) | ||||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Hôpital Lariboisière - 75010 - Paris - France | Eric JOUVENT, PhD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Age 18 years and above
- History of recent (less than 15 days) neurological deficit related to a small
subcortical infarct (evidenced by medical history or physical examination)
- Diagnosis of recent small subcortical infarct on MRI (hyperintensity on
diffusion-weighted imaging showing an infarction in the territory of one perforating
artery) presumably responsible for the corresponding neurological deficit
- Lesion diameter mess than 20 mm
- Ability to comply with scheduled follow-up and annual neurological evaluation
- Affiliation to the national French health insurance (sécurité sociale)
- Signature of informed consent
- Age 18 years and above
- History of recent (less than 15 days) neurological deficit related to a small
subcortical infarct (evidenced by medical history or physical examination)
- Diagnosis of recent small subcortical infarct on MRI (hyperintensity on
diffusion-weighted imaging showing an infarction in the territory of one perforating
artery) presumably responsible for the corresponding neurological deficit
- Lesion diameter mess than 20 mm
- Ability to comply with scheduled follow-up and annual neurological evaluation
- Affiliation to the national French health insurance (sécurité sociale)
- Signature of informed consent
- Prior diagnosis of dementia according to DSM IV criteria
- Prior severe disability with Rankin scale ≥ 4
- Serious concomitant systemic disorder that can compromise the follow-up study;
- Leukoencephalopathy of non-vascular origin;
- Severe psychiatric disorder;
- Inability to obtain an informed signed consent from the patient or his/her family;
- Medical contraindication or refusal to undergo cerebral magnetic resonance scanning
(MRI).