Informations générales (source: ClinicalTrials.gov)
Extern Validation of a Predictive Score of Brain Death in Patients With Severe Stroke and Unfavourable Prognosis Identified by Organ Procurement and Transplant Coordinations (DIAPASON1)
Observational
Central Hospital, Nancy, France (Voir sur ClinicalTrials)
février 2019
octobre 2021
29 juin 2024
There is currently a shortage of organ in France, for patients with chronic diseases who
are on the waiting list for an organ. The first source of organ donor in France is
patients with brain death. 58% of patients in brain death are patients with a severe
stroke ( ischemic or hemorrhagic). In order to identify which patient with a severe
stroke and with unfavorable prognosis who can evolve to brain death, we have conducted a
retrospective study in Lorrain, in France, and we have built a predictive score of brain
death in these patients. It is important to validate this predictive score in a
prospective study on a greater scale than the first study.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CH d'Auxerre - Auxerre - France | Contact (sur clinicalTrials) | ||||
| CH de Chalons-en-Champagne - Châlons-en-Champagne - France | Contact (sur clinicalTrials) | ||||
| CH de Charleville-Mézières - Charleville-Mézières - France | Contact (sur clinicalTrials) | ||||
| CH de Colmar - Colmar - France | Contact (sur clinicalTrials) | ||||
| Ch de Compiègne - Compiègne - France | Contact (sur clinicalTrials) | ||||
| CH de Laon - Laon - France | Contact (sur clinicalTrials) | ||||
| CH de Macon - Mâcon - France | Contact (sur clinicalTrials) | ||||
| CH de saverne - Saverne - France | Contact (sur clinicalTrials) | ||||
| CH Epinal - Épinal - France | Contact (sur clinicalTrials) | ||||
| CH Nevers - Nevers - France | Contact (sur clinicalTrials) | ||||
| CH Sarreguemines - Sarreguemines - France | Contact (sur clinicalTrials) | ||||
| CH Troyes - Troyes - France | Contact (sur clinicalTrials) | ||||
| CH Verdun - Verdun - France | Contact (sur clinicalTrials) | ||||
| CHR Metz-Thionville - Metz - France | Contact (sur clinicalTrials) | ||||
| CHRU de Nancy - Nancy - France | Lisa Humbertjean-Selton | Contact (sur clinicalTrials) | |||
| CHU de Dijon - Dijon - France | Contact (sur clinicalTrials) | ||||
| Hôpital Nord Franche - Belfort - France | Contact (sur clinicalTrials) | ||||
| Lons Le Saunier - Lons-le-Saunier - France | Contact (sur clinicalTrials) | ||||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| CH de Haguenau - Haguenau - France | Contact (sur clinicalTrials) | ||||
| CH de Mulhouse - Mulhouse - France | Contact (sur clinicalTrials) | ||||
| CH de Saint-Quentin - Saint-Quentin - France | Contact (sur clinicalTrials) | ||||
| CH de Vesoul - Vesoul - France | Contact (sur clinicalTrials) | ||||
| CHRU de Strasbourg - Strasbourg - France | Contact (sur clinicalTrials) | ||||
| CHU Besançon - Besançon - France | Contact (sur clinicalTrials) | ||||
| CHU de Reims - Reims - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
Inclusion Criteria:
- Patient aged 18 years and over.
- Patient with a sever stroke less than 48 hours diagnosed by brain imaging magnetic
resonance imaging or computed tomography (including cerebral infarction,
intra-parenchymal hemorrhage and subarachnoid haemorrhage
- Patient with Glasgow Scale score <8 Engaged vital prognosis
- Absence of therapeutic resources
- Decision of resuscitation measures to protect the organs in the purpose organ
donation after brain death
- Patient aged 18 years and over.
- Patient with a sever stroke less than 48 hours diagnosed by brain imaging magnetic
resonance imaging or computed tomography (including cerebral infarction,
intra-parenchymal hemorrhage and subarachnoid haemorrhage
- Patient with Glasgow Scale score <8 Engaged vital prognosis
- Absence of therapeutic resources
- Decision of resuscitation measures to protect the organs in the purpose organ
donation after brain death
- Pregnant woman
- Patient with recent traumatic brain injuries (subdural hematoma, extradural hematoma
and contusions)
- Obvious contraindication of organ donation excluding the patient from organ
protection measures in intensive care unit (expression of patient opposition, HIV
infection, active tuberculosis, spongiform encephalopathy,
- human growth hormones treatment origin, rabies, active cancer)
- Opposition of family member of the patient