Informations générales (source: ClinicalTrials.gov)

NCT03622333 En recrutement IDF
Clinic, Pathologic and Genetic Characterization of Patients With Familial Carcinoid Tumors (Study From the GTE, Groupe d'étude Des Tumeurs Endocrines)
Interventional
  • Tumeur carcinoïde
N/A
CHU de Reims (Voir sur ClinicalTrials)
mai 2018
novembre 2022
05 avril 2025
Small intestine carcinoid tumors are rare. Small intestine Familial Carcinoid Tumors (FCT) are defined by the occurrence of at least 2 cases of this tumor type in first- or second-degree relatives. The estimated prevalence of FCT is 2.6%-3.7% in patients with small intestine carcinoid tumors. Because of its rarity, epidemiologic, clinic and pathologic features of FCT have been scarcely described. Molecular abnormalities associated with FCT have been poorly explored. Constitutional genetic factors predisposing to FCT have not been discovered to date. Only one abnormality (mutation of the IPMK gene) has been reported in one FCT family only, but not found in other series. The main objective of this study is to identify the constitutional factors predisposing to small-intestine FCT (and other midgut localizations: ascending colon and appendix). The secondary objectives are to describe the clinic and pathologic features associated with FCT.
 Voir le détail

Etablissements

Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données
CLCC INSTITUT CURIE En recrutement IDF 10/04/2025 13:12:16 Contact (sur clinicalTrials)
CLCC RENE HUGUENIN INSTITUT CURIE En recrutement IDF 07/08/2024 08:21:58 Contact (sur clinicalTrials)
Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
Damien JOLLY - Reims - France Guillaume CADIOT En recrutement Contact (sur clinicalTrials)

Critères

Tous
inclusion criteria :

- Small-intestine (or ascending colon or appendix) neuroendocrine tumor (proven
histologically)

- At least one first- or second-degree relative with a small-intestine (or ascending
colon or appendix) neuroendocrine tumor (proven histologically)

- Agreement to participate to the study exclusion criteria :

- Subjects unable to provide consent