Informations générales (source: ClinicalTrials.gov)
Value of Tomosynthesis for Detection of Sacro-iliitis: a Prospective Comparative Study (TOMOS SI)
Interventional
N/A
University Hospital, Montpellier (Voir sur ClinicalTrials)
octobre 2018
décembre 2020
29 juin 2024
Spondyloarthropathies (SpAs) are chronic inflammatory diseases encompassing ankylosing
spondylitis, psoriatic arthritis, reactive arthritis, enteropathic arthropathy, and
undifferentiated SpA.
In 2001, the estimated prevalence of SpA was 1.5% worldwide. Sacroiliitis is a condition
caused by inflammation within the sacroiliac joint. It is the most frequent damage of SpA
depicted at imaging evaluation.
Conventional radiography (X-ray) is usually used to depict the structural changes
associated with sacroiliitis.
However further evaluation often requires additionnal computed tomography (CT).
Tomosynthesis is an Xray-based imaging technology which allows reconstruction of multiple
section images from a set of projection images acquired as the x-ray tube moves along a
prescribed path. The advantagee of tomosynthesis is the significant reduction of
radiation dose exposure compared to CT Tomosynthesis is currently used in the field of
breast imaging and pneumology. Very few studies have examined the value of tomosynthesis
for osteoarticular imaging.
The study aims at evaluating the diagnostic performances of tomosynthesis as compared to
standard X-ray and CT, in patients with a clinical suspicion of sacroiliitis.
the investigators hypothesize that tomosynthesis is superior to conventional radiography
for detection of sacroiliitis and is at least equal to CT with lower irradiation.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Imaging department- University hospital - 34295 - Montpellier - France | Sophie Lefebvre | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Patients aged 18 and over referred for suspected sacroiliitis.
- Patients who have entered into their participation agreement by signing the informed
consent form.
- Patient affiliated to a social security scheme or beneficiary.
- Patients aged 18 and over referred for suspected sacroiliitis.
- Patients who have entered into their participation agreement by signing the informed
consent form.
- Patient affiliated to a social security scheme or beneficiary.
- Pregnant or lactating women.
- Vulnerable people according.
- Major people placed under guardianship or curatorship.