Informations générales (source: ClinicalTrials.gov)
How Nicardipine and Labetalol Affect Cerebral Hemodynamics in Severe Preeclamptic Patients: A Pilot Observational Study (PREMODYM)
Observational [Patient Registry]
Hopital Antoine Beclere (Voir sur ClinicalTrials)
novembre 2018
mai 2019
29 juin 2024
Realization of transcranial doppler and optic nerve sheath in severe preeclamptic
patients to evaluate the impact of nicardipine and labetalol on cerebral hemodynamics.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Hôpital Béclère - 92140 - Clamart - France | Mickaël SOUED | Contact (sur clinicalTrials) | |||
Critères
Femme
Inclusion Criteria:
- Aged up to 18 years
- patient with severe preeclampsia defined by Systolic blood pressure ≥ 140 mmHg
and/or diastolic blood pressure ≥ 90 mmHg after 20 weeks of amenorrhea, associated
with neurologic troubles, eclampsia of epigastric pain.
- Decision by clinician to introduce an antihypertensive therapy by oral route :
either labetalol or nicardipine
- Aged up to 18 years
- patient with severe preeclampsia defined by Systolic blood pressure ≥ 140 mmHg
and/or diastolic blood pressure ≥ 90 mmHg after 20 weeks of amenorrhea, associated
with neurologic troubles, eclampsia of epigastric pain.
- Decision by clinician to introduce an antihypertensive therapy by oral route :
either labetalol or nicardipine
- history of intracranial expansive processus, surgery or vascular disease
- infectious state on probe placement
- unilateral anophthalmia