Informations générales (source: ClinicalTrials.gov)

NCT03863782 En recrutement
Lyon Sarcoid Uveitis Cohort (LUCS)
Observational
  • Sarcoïdose
  • Uvéite
Hospices Civils de Lyon (Voir sur ClinicalTrials)
janvier 2016
janvier 2025
29 juin 2024
Sarcoidosis is a systemic disease with unknown etiology. Chronicity of the disease is observed in 1/3 of cases. Five percent of the affected patients are expected to die due to pulmonary worsening. After pulmonary complications, ocular complications are one of the most frequent complications. In hospital setting 2 to 15% of patients who come for initial uveitis diagnosis are after examination due to Sarcoidosis. Sarcoidosis diagnosis is based on paraclinical exams (biological, radiography) and histological confirmation. Corticotherapy (local or general) is usually used to cure sarcoid uveitis. In case of failure immunosuppressor or anti-tumor necrosis factor (TNF) can be used. In 10% of cases ocular symptoms including blindness are observed. Only treatment administrated quickly after diagnosis of sarcoid uveitis can prevent from ophthalmologic complications. The main objective of the Lyon Sarcoid Uveitis Cohort study is to analyze the relevance of the paraclinical exam for sarcoid uveitis diagnosis, and to define a better visual and extra-ophthalmologic prognosis and describe the therapeutic practice in our Department. This study is proposed to all patients diagnosed with Sarcoid uveitis with a histological confirmation and referred to the internal medicine department of the Croix-Rousse hospital, Lyon, France, for etiologic diagnosis or treatment.

Etablissements

Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
Hospices Civils de Lyon - Lyon - France Pascal SEVE En recrutement Contact (sur clinicalTrials)

Critères

Tous
Inclusion Criteria:

- Diagnosis of sarcoid uveitis

- First consultation in the department of Internal Medicine at the Croix-Rousse
hospital, Lyon, France



- None