Informations générales (source: ClinicalTrials.gov)
Study of Clinical Profiles of Patients Followed for Chronic Hypereosinophilia and/or Hypereosinophilic Syndrome by the Creation of a National Cohort
Observational
University Hospital, Lille (Voir sur ClinicalTrials)
mai 2019
mai 2031
02 mars 2026
Unexplained chronic hypereosinophilia (HE) and hypereosinophilic syndromes (HES) are
heterogeneous regarding the organ involvements (heart, lungs, skin, .. or none), the
evolutionary profiles, the response to treatments.
Underlying mechanisms are largely unknown and may associate genetic predisposing factors
(germinal ? somatic?), environmental factors (alimentation, tobacco use, hormones,
infections, ..) The COHESion study aims to study all clinical and biological
characteristics of HE/HES patients and their evolutionary profiles, with a focus on
genetic factors and the mechanisms supporting transitory or persistant chronic HE/HES (in
absence of any well identified extrinsic trigger like drugs, parasitosis, ..)
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL FOCH | Matthieu GROH | 11/05/2026 07:25:43 | Contacter | ||
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Hôpital Roger Salengro, CHU - Lille 2998324 - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
- Men or Women of any age :
- With the diagnosis criteria of hyperosinophlia OR hypereosinophilic syndrome OR
specific organ eosinophilic disease according to the consensus conference of the
International Cooperative Working Group on Eosinophil Disorders (ICOG-EO)
- With an AEC > 1500/mm3 or organ damage related to the presence of eosinophils in the
tissues or organs whatever the context (idiopathic, clonal or reactive, including
drug-related, parasitic or allergic)
- HES diagnosis since 2005/01/01
- Patients socially insured
- Patient who agreed to participate to the study, its proceedings and duration.
Exclusion Criteria:
- Known HIV infection
- Not socially insured
- Person unable to receive a enlighten information
- Person who refuse to sign the consent
- Persons deprived of their liberty
- Persons benefiting from a system of legal protection (tutelage / guardianship)