Informations générales (source: ClinicalTrials.gov)
Assessment of Venous Drainage in Idiopathic Intracranial Hypertension (HYPERPIC)
Interventional
N/A
Centre Hospitalier Universitaire, Amiens (Voir sur ClinicalTrials)
février 2020
octobre 2023
08 mars 2025
Intracranial hypertension (IIH) is a disorder producing a syndrome of increased
intracranial pressure secondary to a compressive intracranial lesion or said to be
idiopathic. The most common symptoms are headaches, blindness, pulsatile tinnitus or
papillary edema. There are many options for the treatment of IIH, especially neurosurgery
(derivation of cerebrospinal fluid or stent placement). Currently, idiopathic IIH has no
clear etiology but the hypothesis of sino-venous insufficiency is more and more
recognized. The assumption of venous insufficiency has not been demonstrated so far.
Therefore the investigators propose to demonstrate that cerebral venous drainage pathways
are altered in adult patients with idiopathic intracranial hypertension in comparison to
healthy individuals having normal circulation. Assessment will be performed using
Magnetic Resonance Imaging which is part of the patient care.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU Amiens - 80480 - Salouël - France | Olivier Baledent, DR | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Age : >18 years old
- adult patients referred to the imaging department for intracranial hypertension
assessment
- adult control subjects without history of cerebral or vascular pathology
- Age : >18 years old
- adult patients referred to the imaging department for intracranial hypertension
assessment
- adult control subjects without history of cerebral or vascular pathology
- history of cerebral or vascular pathology for the control subjects
- pregnant woman
- claustrophobia
- major obesity
- any contraindication to MRI exam