Informations générales (source: ClinicalTrials.gov)
LUMIERE on the FETUS : A Study on the Added Value of Fetal MRI
Observational
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
décembre 2019
juin 2027
02 décembre 2025
Congenital anomalies are a major public health problem. They affect 2-3% of births,
around 20,000 new cases per year in France, of which 15% are cared for in Ile de France.
These congenital anomalies are a major cause of morbidity, infant mortality and
disability. They are also a major cause of death during the infant period (22% of deaths
during the first year of life: source CépiDC Inserm 2010). The detection, accurate
diagnosis and accurate prognosis, particularly functional, of these congenital anomalies
are still difficult in the current monitoring of pregnancy, which is based primarily on
ultrasound. The use and development of modern imaging techniques is now essential to
enable doctors to better see and better examine the fetus. Alongside ultrasound, Magnetic
Resonance Imaging (MRI) is a technique that has undergone significant development in
recent years. MRI must allow the effective anatomical and functional evaluation of the
main fetal organs and could in particular be interesting in several situations in which
it has not yet been sufficiently evaluated and is not yet performed in clinical routine.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP Assistance publique - Hôpitaux de Paris | 13/12/2025 07:23:24 | Contacter | |||
| AP-HP - Hôpital Necker-Enfants Malades | |||||
| AP-HP - Hôpital Necker-Enfants Malades | |||||
Critères
Femme
- patient ≥ 18 years
- Single or twin pregnancy
- gestational age≥ 16 WG and ≤ 36 WG based on cranio-caudal length (LCC) dating
- Collection of the patient's consent
Exclusion Criteria:
contraindication to MRI
- multiple pregnancies > 2
- subsequent follow-up impossible
- maternal condition contraindicates continuation of pregnancy
- patient having to have an MRI examination as part of the normal clinical follow-up
of her pregnancy (identified or strongly suspected echocardiographic abnormality on
ultrasound, diaphragmatic dome hernia, CMV fetal infection, antecedent brain
abnormality in siblings, STT operated)