Informations générales (source: ClinicalTrials.gov)
Efficacy of Repeated Locoregional Anesthetics Blocks With Bupivacaine in Patients Suffering of Chronic Dentoalveolar Pain. (BADDAP) (BADDAP)
Interventional
Phase 2
University Hospital, Clermont-Ferrand (Voir sur ClinicalTrials)
août 2020
octobre 2023
29 juin 2024
The aim of this study is to evaluate the efficacy of anesthetic blocks repeated with
bupivacaine in the management of patients with persistent dentoalveolar pain. Goals are
to improve the understanding of the physiopathological mechanisms of persistent
dentoalveolar pain and to highlight predictive criteria for the effectiveness of
anesthetic blocks.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU de Clermont-Ferrand - 63000 - Clermont-Ferrand - France | Lise Laclautre, Pharm D | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Patient, male or female, over 18, with persistent dentoalveolar pain defined
according to the criteria:
- daily presence (> 2 hours / day and for more than 3 months) and continues pain;
- located at one or more teeth or at the level of the alveolar bone;
- not following a nervous path;
- clinical, radiological and neurological examinations showing no cause organic
visible;
- dental causes excluded by appropriate tests;
- local or systemic pathologies related to pain apart.
- Pain intensity greater than or equal to 4/10 on numerical scale
- Patient informed of the constraints of the study and having given his written
consent. Benefiting of a social security scheme.
- Mastering correctly French.
- Patient, male or female, over 18, with persistent dentoalveolar pain defined
according to the criteria:
- daily presence (> 2 hours / day and for more than 3 months) and continues pain;
- located at one or more teeth or at the level of the alveolar bone;
- not following a nervous path;
- clinical, radiological and neurological examinations showing no cause organic
visible;
- dental causes excluded by appropriate tests;
- local or systemic pathologies related to pain apart.
- Pain intensity greater than or equal to 4/10 on numerical scale
- Patient informed of the constraints of the study and having given his written
consent. Benefiting of a social security scheme.
- Mastering correctly French.
- Pregnant women, breastfeeding, or likely to be pregnant.
- Oral pain of known origin (cancerous, infectious, traumatic).
- Patient having modified (stopped, started or modified dosage) in the last 2 month
local or systemic medication that may interfere with the study results (for example,
patients taking long-range psychotropic drugs will not be excluded).
- All medical pathology judged by the investigator as not compatible with the study.
- Known hypersensitivity to local amide-bound anesthetics or to any of the excipients
- Treatment anticoagulant or known disorder of blood
- Porphyria.
- Atrioventricular conduction requiring training permanent electrosystol not yet
realized.
- Epilepsy not controlled by a treatment.
- Patient non-cooperating, not speaking or not reading fluently French or in the
impossibility of understanding the principle of a pain scale or understanding the
study or to sign an informed consent.
- Patient under guardianship, curatorship, or deprived of liberties.