Informations générales (source: ClinicalTrials.gov)
Study of Electrophysiological Markers Related to the Cognitive and Affective Processes Behind Empathic Behaviour in Schizophrenic Spectrum Disorder (SchizoEmp)
Interventional
N/A
Centre Hospitalier Universitaire de Nice (Voir sur ClinicalTrials)
octobre 2020
octobre 2026
05 avril 2025
Disorders of social cognition, and empathy more specifically, are at the heart of
schizophrenic pathology in that they are strongly linked to the social handicap of
patients. It is therefore necessary to refine our knowledge of the cognitive and
affective processes behind this empathic disorder and to identify objective and easily
measurable markers (related to brain functioning collected by electroencephalography) of
these processes with the subsequent aim of improving their management. It is also
relevant to question the trait/status nature of these empathic disorders by studying
these markers in individuals presenting more or less marked schizotypic traits and
therefore more or less at risk of developing schizophrenia. Studying the possibility that
empathy disorders may be part of the factors of developmental vulnerability for
schizophrenia and identifying objective markers of this vulnerability could allow, in
case of development of the pathology, a more rapid diagnosis and a more effective
management.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Hôpital Pasteur - Service de Psychiatrie - 06001 - Nice - France | Bruno GIORDANA, PH | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Common to all: good command of the French language, right-handed.
- Specific to patients: diagnosis of schizophrenia or schizoaffective disorder,
clinical state stabilized according to the treating psychiatrist.
- Common to all: good command of the French language, right-handed.
- Specific to patients: diagnosis of schizophrenia or schizoaffective disorder,
clinical state stabilized according to the treating psychiatrist.
- Common to all: having suffered a head injury with loss of consciousness lasting more
than 5 minutes, participating in another project at the time of the present study,
presenting an addiction to a toxic substance (excluding tobacco), presenting a
mental retardation or neurological disorder (verified by a pre-recruitment interview
and the administration of the Mini International Neuropsychiatric Interview for
control subjects and on the basis of the information in the medical file for
patients).
- Patient-specific: significant change (according to the doctor) in treatment in the
previous month, currently hospitalized.
- Specific to controls: taking a psychoactive drug, having a mental disorder, being
first-degree related to a patient with a disorder other than schizophrenia or
schizoaffective disorder.