Informations générales (source: ClinicalTrials.gov)
Prospective Cohort of Patients With Hepatocellular Carcinoma in France (CHIEF)
Observational
Centre Hospitalier Universitaire, Amiens (Voir sur ClinicalTrials)
août 2019
décembre 2027
29 juin 2024
Hepatocellular carcinoma (HCC) occurs in 90% of cirrhosis primary liver cancers. In
France, 8,500 new cases of HCC occur each year, and about 8,000 deaths per year are
related to this cancer. The 5-year survival rate is 10%, one of the lowest survival rates
of all cancer types. HCC raises a number of major challenges: HCC is discovered at a
curable stage in only 25% of cases, reflecting the marked delay in the diagnosis of early
stages. The state of knowledge about HCC is well behind that of other cancers (no
biomarker, complex carcinogenesis, influence of the aetiology, poorly valorised data,
etc.). Rapid technological progress requires large-scale studies to evaluate new
diagnostic and therapeutic modalities.
The CHIEF project constitutes a common basis knowledge for research project using
prospectively collected data in patients with HCC, regardless of the cause and stage of
the cancer.
This project is a Multicentre longitudinal observational study of patients with HCC with
prospective data collection on inclusion and patient follow-up. Constitution of a
biological resources collection. 5,000 patients will be included over 2 years with a
follow-up of patients of 5 years.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHI DE CRETEIL | Isabelle ROSA | 29/03/2024 01:29:39 | Contacter | ||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| CHU Amiens - 80480 - Amiens - France | Olivier Ganry, Pr | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- New cases of HCC
- suspected case of HCC regardless of the cause, stage, treatment
- Known HCC: drug treatment for recurrence or progression
- New cases of HCC
- suspected case of HCC regardless of the cause, stage, treatment
- Known HCC: drug treatment for recurrence or progression
- Associated serious condition threatening life in the short term (with the exception
of liver disease itself)
- So-called vulnerable populations: minors, persons under guardianship or temporary
guardianship, or person deprived of their liberty by an administrative or judicial
decision