Informations générales (source: ClinicalTrials.gov)

NCT04350710 Statut inconnu
Evaluation of Respiratory Mechanics and Lung Recruitment in Patients With SARS-CoV-2 Associated Acute Respiratory Distress Syndrome
Observational
  • Syndrome de détresse respiratoire du nouveau-né
  • Syndrome de détresse respiratoire de l'adulte
  • Syndrome
  • Lésion pulmonaire aigüe
University Hospital, Angers (Voir sur ClinicalTrials)
mars 2020
décembre 2020
29 juin 2024
The aim of this observationnal study is to describe respiratory mechanics and lung recruitement in patients with SARS-CoV-2 Associated Acute Respiratory Distress Syndrome who underwent invasive ventilation on endotracheal tube, admitted to the medical ICU of Angers university hospital . Statics measurements of respiratory system compliance were performed at 2 differents levels of PEEP (15 cmH2O and 5 cmH2O). The recruited volume is computed as the difference between the volume expired from PEEP 15 to 5 cmH2O and the volume predicted by compliance at PEEP 5 cmH2O . The recruitment-to-Inflation (R/I) ratio (i.e. the ratio between the recruited lung compliance and CRS at PEEP 5 cmH2O) is used to assess lung recruitability. A R/I ratio value higher than or equal to 0.5 was used to define highly recruiter patients.
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Etablissements

Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données
CHU - 49100 - Angers - France Francois BELONCLE, MCU-PH En recrutement Contact (sur clinicalTrials)

Critères

Tous
Inclusion Criteria:

- ARDS criteria according to Berlin classification criteria

- Invasive mechanical ventilation on endotracheal tube

- SARS Cov-2 infection


- pneumothorax