Informations générales (source: ClinicalTrials.gov)
Clinical Characterisation Protocol for COVID-19 in People Living With HIV
Observational
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
avril 2020
octobre 2020
11 septembre 2025
There is very little data so far to determine whether people living with HIV (PLWHIV) are
at greater risk of COVID-19 acquisition or severe disease. HIV infection is associated
with deficiencies in both humoral and cell-mediated immunity that could potentially alter
the course and severity of common infections. The investigators will study the
correlation between clinical and immunovirological data. The singularity of this work is
to have an in-depth immunovirological approach linked to the clinical characteristics in
COVID-19 HIV co-infected patients. COVIDHIV is the only study to date to offer this
combined approach in PLWHIV.
This protocol is a historical and prospective cohort study of PLWHIV presenting COVID-19
The primary objectives are to describe the course of COVID-19 disease in patients
infected with HIV
Etablissements
Critères
Tous
Inclusion Criteria:
Inclusion criteria for the 250 patients with COVID19
- Patient living with HIV (PLWHIV)
- Patient with confirmed infection with SARS-CoV-2 since 1st January 2020 with and
without criteria of hospitalisation.
Inclusion criteria for the 20 patients without COVID19 (who will only realize the
qualitative interview)
- Patient living with HIV (PLWHIV)
- Patient who did not have COVID-19
Inclusion criteria for the 250 patients with COVID19
- Patient living with HIV (PLWHIV)
- Patient with confirmed infection with SARS-CoV-2 since 1st January 2020 with and
without criteria of hospitalisation.
Inclusion criteria for the 20 patients without COVID19 (who will only realize the
qualitative interview)
- Patient living with HIV (PLWHIV)
- Patient who did not have COVID-19
Exclusion criteria for the 250 patients with COVID19
- Confirmed diagnosis of another pathogen than SARS-CoV-2
- Refusal by participant, or appropriate representative.
- Being under guardianship or trusteeship mandate for future protection
- Participate to another study without consent of the promoter
- Patients less than 18 years old
- No Beneficiary or entitled to a social security scheme or state medical aid.
Exclusion criteria for the 20 patients without COVID19 (who will only realize the
qualitative interview)
- Refusal by participant, or appropriate representative.
- Being under guardianship or trusteeship mandate for future protection
- Participate to another study without consent of the promoter
- Patients less than 18 years old
- No Beneficiary or entitled to a social security scheme or state medical aid.