Informations générales (source: ClinicalTrials.gov)
Ex Vivo Study of Drugs Transfer Across the Placenta (DRUGS-PTP)
Observational
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
juin 2020
juin 2030
29 juin 2024
Drug prescriptions are usual during pregnancy however women and their fetuses still
remain an orphan population with regard to drugs efficacy and safety clinical studies.
Most xenobiotics diffuse through the placenta and some of them can alter fetus
development resulting in structural abnormalities, growth or functional deficiencies. The
aim of the study is to study the drug transfer using human placenta after delivery.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Cochin | TRELUYER Jean-marc | 18/04/2025 07:55:21 | Contacter | ||
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| CRF PORT ROYAL | Camille LE RAY | Contact (sur clinicalTrials) | |||
Critères
Femme
Inclusion Criteria:
- pregnant women older than 18 years,
- patient with social security or health insurance,
- from the 24th week of amenorrhea,
- patient who has given her consent,
- pregnant women older than 18 years,
- patient with social security or health insurance,
- from the 24th week of amenorrhea,
- patient who has given her consent,
- Maternal pathologies pre-existing pregnancy :
- diabetes-like vascular disease,
- arterial hypertension,
- known prothrombotic pathology, history of venous thrombosis or pulmonary
embolism,
- maternal serology HIV+, BHV+, CHV+ and syphilis,
- Pregnancy and fetal pathologies :
- pre-eclampsia,
- delayed growth in utero (can affect placental circulation),
- gestational diabetes without insulin,
- fetal malformation,
- known genetic pathology,
- Patient under tutorship or curatorship, or not speaking french,
- Patient who has not given her consent