Informations générales (source: ClinicalTrials.gov)
ARTERIAL EMBOLIZATION OF PERSISTENT GENICULATE ARTERIES FOR CHRONIC PAIN MANAGEMENT AFTER TOTAL KNEE-REPLACEMENT ARTHROPLASTY: A FEASIBILITY STUDY (KNEE EMBOLISATION)
Interventional
N/A
Assistance Publique Hopitaux De Marseille (Voir sur ClinicalTrials)
juin 2021
février 2024
29 juin 2024
Recent works in interventional radiology have shown interesting results in the treatment
of musculoskeletal inflammatory sites by arterial embolization. Supra-selective arterial
embolization has been successfully developed by Dr. Okuno (Japan) to manage moderate to
severe knee osteoarthritis. Also, inflammation of the surgical site mediated via
geniculate arteries is a major cause for persistent chronic post-operative gonalgia.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Assistance Publique Hopitaux de Marseille - 13354 - Marseille - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
Inclusion Criteria:
- Adult patient (male or female) aged 18-85
- Suffering from moderate to severe chronic pain (EVA > 50mm) more than 6 months after
total prosthetic knee replacement surgery for severe gonarthrosis with impact on
quality of life.
- And having followed for at least 3 months a well-conducted conservative medical
treatment (anti-inflammatory, analgesic, masso-kinesiotherapy).
- The patient may initially have had a single or bilateral replacement. The period of
6 months must be respected for each side, between the intervention and the inclusion
for homolateral pain.
- Patient willing to participate in the study and with signed informed consent.
- Patient willing to undergo post-operative monitoring for one year.
- Adult patient (male or female) aged 18-85
- Suffering from moderate to severe chronic pain (EVA > 50mm) more than 6 months after
total prosthetic knee replacement surgery for severe gonarthrosis with impact on
quality of life.
- And having followed for at least 3 months a well-conducted conservative medical
treatment (anti-inflammatory, analgesic, masso-kinesiotherapy).
- The patient may initially have had a single or bilateral replacement. The period of
6 months must be respected for each side, between the intervention and the inclusion
for homolateral pain.
- Patient willing to participate in the study and with signed informed consent.
- Patient willing to undergo post-operative monitoring for one year.
Orthopaedic or rheumatological pathologies:
- Rheumatoid arthritis
- Psoriatic rheumatism
- Spondylarthropathies
- History of primary or secondary bone tumor, in remission or active.
- Myeloma
- Operational criteria:
- Infection of the surgical site
- Re-operation
- Severe bleeding
- Use of turnstile per-operative
- Wound of popliteal artery
- Diabetic patient
- Comorbidities:
- General condition responsible for objective hemostasis disorder (hemophilia,
Willebrand disease, thrombocytopenia) and anticoagulant treatments.
- Pads 100 G/L