Informations générales (source: ClinicalTrials.gov)
Self-administered Hyperinsufflation Chest Mobilization Randomized Study on the Risk of Low Respiratory Infection in Patients With Multiple Sclerosis With Sputum Capacity Deficit
Interventional
N/A
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
novembre 2021
octobre 2022
03 décembre 2025
In patients with neuromuscular disease, chest mobilization by hyperinsufflation slows
respiratory decline by almost 80% compared to controls, and prevents complications like
pneumonia, atelectasis and respiratory distress.
This insufflation technique improves the airway clearance and reduces the need for
invasive ventilation. It also improves CV and DEPtoux in patients with neuromuscular
pathology
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP Assistance publique - Hôpitaux de Paris | 13/12/2025 07:22:35 | Contacter | |||
| AP-HP - Hôpital Raymond Poincaré | |||||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Hôpital Raymond Poincaré - 92380 - Garches - Haut De Seine - France | Jonathan LEVY, Dr | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Confirmed MS diagnosis (McDonald criteria)
- EDSS ≥ 7
- Age greater than or equal to 18 years.
- Expiratory flow during a coughing effort (DEPtoux) ˂4.5L / s.
- Confirmed MS diagnosis (McDonald criteria)
- EDSS ≥ 7
- Age greater than or equal to 18 years.
- Expiratory flow during a coughing effort (DEPtoux) ˂4.5L / s.
- ENT and / or thoracic surgery less than 6 months old
- Progressive or past pneumothorax / pneumomediastinum
- Severe swallowing disorders.
- Inability to use the device under study