Informations générales (source: ClinicalTrials.gov)

NCT04615221 En recrutement IDF
Immunological Mechanisms of Rejection in Uterine Transplantation (MARNI)
Interventional
N/A
Hopital Foch (Voir sur ClinicalTrials)
septembre 2020
septembre 2028
29 juin 2024
The objective of this study is to understand the mechanisms of rejection in uterine transplantation and to search for non-invasive markers of rejection. The biological samples necessary for our research have been or will be collected during procedures (biopsies, smears, vaginal swab, blood tests) carried out as part of the scheduled follow-up of patients. These will be samples whose collection is minimally or not invasive
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Etablissements

Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données
HOPITAL FOCH Marie CARBONNEL En recrutement IDF 05/05/2025 07:12:08  Contacter

Critères

Femme
Inclusion Criteria:

- Patient going to or having received a uterine transplant OR Patient going to or
having donated a uterus for a recipient included in the study OR Premenopausal woman
to undergo gynecological surgery under general anesthesia: for 4 of them it was a
hysterectomy and they must be under 45 years old, the other 6 must be under 38 years
old.

Exclusion Criteria (For witness):

- Pregnancy in progress

- Current infection

- Cervical dysplasia

- History of transplant or transfusion

- Cancer or history of cancer

- Menopause

- Patient aged 38 or over for the 6 controls without hysterectomy, patient aged 45 or
over for the 4 patients with hysterectomy.

- Endometriosis