Informations générales (source: ClinicalTrials.gov)
Value of the Laparoscopic Approach in the Surgical Management of Resectable Hepatocellular Carcinoma: a Randomized Controlled Trial (LapCHC)
Interventional
N/A
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
mai 2021
mai 2026
29 juin 2024
Hepatocellular carcinoma treated by laparotomy or laparoscopic Multicenter prospective,
open, superiority, controlled, randomized, clinical trial The primary objective of the
study will be to demonstrate the superiority of the laparoscopic approach over the open
approach in reducing postoperative morbidity in HCC patients.
Postoperative morbidity will be assessed using the Comprehensive Complication Index (CCI)
within 90 days postoperatively or at any time during hospitalization
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Beaujon | DOKMAK Safi | 18/04/2025 07:55:17 | Contacter | ||
| AP-HP - Hôpital Cochin | DOKMAK Safi | 18/04/2025 07:55:17 | Contacter | ||
| AP-HP - Hôpital Henri Mondor-Albert Chenevier | DOKMAK Safi | 18/04/2025 07:55:17 | Contacter | ||
| AP-HP - Hôpital La Pitié-Salpêtrière | DOKMAK Safi | 18/04/2025 07:55:17 | Contacter | ||
| AP-HP - Hôpital Paul Brousse | DOKMAK Safi | 18/04/2025 07:55:17 | Contacter | ||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Chirurgie Digestive - CHU Amiens - 80054 - Amiens - France | REGIMBEAU Jean Marc | Contact (sur clinicalTrials) | |||
| Chirurgie Digestive - CHU Montpellier - 34090 - Montpellier - France | HERRERO Astrid | Contact (sur clinicalTrials) | |||
| Chirurgie Digestive - Hôpital La Timone - 13005 - Marseille - France | Contact (sur clinicalTrials) | ||||
| Chirurgie digestive - Institut Mutualiste Montsouris - 75014 - Paris - France | SOUBRANE Olivier | Contact (sur clinicalTrials) | |||
| Chirurgie Digestive et de l'Urgence - CHU Grenoble - 38700 - Grenoble - France | CHIRICA Mircea | Contact (sur clinicalTrials) | |||
| Chirurgie Digestive et Transplantations - Hôpital Huriez - 59021 - Lille - France | BOLESLAWSKI Emmanuel | Contact (sur clinicalTrials) | |||
| Chirurgie digestive Oncologique Endocrinienne et Transplantation hépatique - CHU Tours - 37000 - Tours - France | BUCUR Petru | Contact (sur clinicalTrials) | |||
| Chirurgie Générale, Digestive et de la Transplantation hépatique - Hôpital de la Croix Rousse - 69317 - Lyon - France | MOHKAM Kayvan | Contact (sur clinicalTrials) | |||
| Chirurgie hépato-biliaire et greffe de foie - La Pitié - 75651 - Paris - France | SCATTON Olivier | Contact (sur clinicalTrials) | |||
| Chirurgie hépato-bilio-pancréatique et Transplantation - Hôpital Rangueil - 31059 - Toulouse - France | Contact (sur clinicalTrials) | ||||
| Chirurgie viscérale et digestive - CHU Besançon - 25000 - Besançon - France | TURCO Celia | Contact (sur clinicalTrials) | |||
| Chirurgie viscérale et digestive - CHU Rouen - 76000 - Rouen - France | SCWARZ Lilian | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Male or female patient aged ≥ 18 years
- Presenting with solitary or multifocal resectable HCC
- Qualifying for both pure laparoscopic and open approaches
- Male or female patient aged ≥ 18 years
- Presenting with solitary or multifocal resectable HCC
- Qualifying for both pure laparoscopic and open approaches
- Physical or psychological status contraindicating the participation to the study
- Contraindication to surgery
- Contraindication to pneumoperitoneum
- ASA (American Society of Anesthesiologists) score IV-V
- Life expectancy < 2 months
- Suspicion of mixed type tumor (Hepatocholangiocarcinoma) and fibrolamellar HCC
- Child-Pugh score > B7
- Extra-hepatic involvement
- Liver resection requiring an associated vascular or biliary reconstruction
- Pregnancy and breast-feeding
- Tutorship, trusteeship
- Concurrent participation in other experimental trials concerning the same objective
within 90 days following intervention
- No Affiliation to the French social security
- No Ability to give their consent and not written informed consent