Informations générales (source: ClinicalTrials.gov)
Diagnostic and Prognostic Biomarkers of Transplant Dysfunction in the Context of Lung Transplantation (DATACOL)
Interventional
N/A
Hopital Foch (Voir sur ClinicalTrials)
mars 2022
mars 2037
29 juin 2024
Transplant results vary considerably from one organ to another. Lung transplantation has
poorer long-term outcomes than other solid organ transplants, with a current median
post-transplant survival of 6.0 years. Allograft rejection remains the leading cause of
morbidity and mortality in all organ groups and is the leading cause of death, accounting
for more than 40% of deaths beyond the first year after lung transplantation.
Each dysfunctions impacts the fate of the graft and therefore the survival of the
recipient. Their early and precise diagnosis is therefore a major issue. The
identification of the pathophysiological mechanisms underlying these different subtypes
of dysfunction (transcriptomics, polymorphism of target genes of the immune system or
tissue repair, cell phenotyping) is an essential step. It can only be done on the basis
of a collection of samples linked to a clinical database allowing to contextualize each
sample.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL FOCH | ANTOINE ROUX | 05/05/2025 07:12:09 | Contacter | ||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Roux - Suresnes - France | Antoine Roux | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Men or women over 15 years of age
- Suffering from a lung condition requiring a transplant planned at Foch Hospital or
being followed up at Foch Hospital following a lung transplant
- Have signed the informed consent form and for patients aged 15 to 18 years that the
person(s) exercising parental authority has/have signed the informed consent.
- Be affiliated with a Health Insurance plan.
- Men or women over 15 years of age
- Suffering from a lung condition requiring a transplant planned at Foch Hospital or
being followed up at Foch Hospital following a lung transplant
- Have signed the informed consent form and for patients aged 15 to 18 years that the
person(s) exercising parental authority has/have signed the informed consent.
- Be affiliated with a Health Insurance plan.
- Pregnant, parturient and/or lactating woman
- Hemoglobin level less than or equal to 8g/dl
- Persons of full age who are subject to a legal protection measure or who are unable
to express their consent
- Persons under the protection of justice
- Not being able to follow the study requirements for geographical, social or
psychological reasons
- Patient refusal.