Informations générales (source: ClinicalTrials.gov)
Feasibility of Using the "CGM GUARDIAN 2" Interstitial Fluid Glucose Measurement System in Intensive Care Medicine (GALI)
Interventional
N/A
Centre Hospitalier Universitaire de Nice (Voir sur ClinicalTrials)
septembre 2023
juin 2025
29 juin 2024
Glycemic imbalances are very common in shock patients admitted to intensive care units. A
blood glucose control every 2 hours is routinely performed in patients requiring insulin
therapy. In practice, we use a protocol and management software called "CPG"
(Personalized Control of Blood Glucose). This involves taking capillary samples from the
fingertips. In addition to the pain generated, local haematomas and sensitivity disorders
have been described. Night-time sampling also leads to repeated awakenings. The "CGM
GUARDIAN 2" system has been validated for the measurement of glucose in interstitial
fluid in insulin-dependent diabetic patients. An electrode is placed on the patient's
abdomen or arm for up to 6 days. This electrode consists of a needle that is inserted
subcutaneously only during the placement. The sugar level is read using a sensor placed
on the electrode and an insulin pump (which will not deliver therapy (for our study) and
which will be used only as an information reader to know the glucose level and trends).
Interstitial fluid is automatically drawn from the electrode every minute and averaged
every 5 minutes.
This device has not yet been validated in resuscitation patients.
Etablissements
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CHU de Nice - Nice - France | Florent BILGER | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Patient in septic shock
- Arterial hypotension requiring noradrenaline
- Hyperglycaemia requiring insulin therapy
- Patient in septic shock
- Arterial hypotension requiring noradrenaline
- Hyperglycaemia requiring insulin therapy
- Patients under guardianship, curatorship or deprived of liberty
- Pregnant or breastfeeding women