Informations générales (source: ClinicalTrials.gov)
Detection of Amyloid Deposits in the Wrist by MRI With Mapping and High Resolution Sequences in Systemic Amyloidosis
Interventional
N/A
GCS Ramsay Santé pour l'Enseignement et la Recherche (Voir sur ClinicalTrials)
janvier 2020
avril 2022
17 juillet 2026
This study is based on the hypothesis that MRI could make it possible to non-invasively
detect these amyloid deposits at the level of the wrist using parametric sequences known
as T1 mapping, in the form of an extension of T1 in the wrists. areas where amyloid
deposits are found in the wrist.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL PRIVE PAUL D EGINE | Contact (sur clinicalTrials) | ||||
Critères
Tous
Patient group:
- Woman or man over 18 years old
- With ATTR or AL cardiac amyloidosis with or without carpal tunnel. The diagnosis of
amyloidosis must be proven by a positive myocardial biopsy or diphosphonate
scintigraphy.
- Affiliate or beneficiarie of a social security scheme.
- Having signed the free and informed consent.
Healthy volunteers:
- Woman or man over 18 years old
- Affiliate or beneficiarie of a social security scheme.
- Having signed the free and informed consent.
Exclusion Criteria:
Patient group:
- Patients participating in another clinical study.
- Patients suffering from rheumatoid arthritis or other autoimmune disease
(vasculitis, lupus, scleroderma, etc.)
- Patients with a medical history of wrist surgery (exclude the operated side).
- Patients with a contraindication to performing an MRI (pacemaker, etc.)
- Pregnant or breastfeeding women.
- Protected patients: Adults under guardianship, curatorship or other legal
protection, deprived of their liberty by judicial or administrative decision.
Healthy volunteer:
- Volunteers participating in another clinical study.
- Volunteers suffering from rheumatoid arthritis or other autoimmune disease
(vasculitis, lupus, scleroderma, etc.)
- Pregnant or breastfeeding women.
- Volunteer with a contraindication to performing an MRI (pacemaker, etc.)
- Protected volunteers: Adults under guardianship, guardianship or other legal
protection, deprived of their liberty by judicial or administrative decision.