Informations générales (source: ClinicalTrials.gov)
Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 70 Years: A Randomized Controlled Trial
Interventional
N/A
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
juin 2022
mai 2030
27 août 2025
The primary objective of DILEMMA study is to assess whether the "heart failure optimal
therapy alone (HFOT)" strategy is non inferior to the "HFOT+ICD" strategy in terms of
overall survival 48 months after randomization, in patients ≥ 70 years with an ICD
indication for primary prevention of SCD whether there is an indication for cardiac
resynchronization therapy or not.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CENTRE CARDIOLOGIQUE DU NORD | MARIJON Eloi | 18/09/2025 17:29:14 | Contacter | ||
| AP-HP Assistance publique - Hôpitaux de Paris | 18/09/2025 17:29:14 | Contacter | |||
| AP-HP - Hôpital Bichat | |||||
| AP-HP - Hôpital Europeen Georges Pompidou | |||||
| AP-HP - Hôpital Henri Mondor-Albert Chenevier | |||||
| AP-HP - Hôpital La Pitié-Salpêtrière | |||||
| Les établissements hors Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:13 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:14 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:14 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:14 | Contact (sur clinicalTrials) | ||||
| 18/09/2025 17:29:14 | Contact (sur clinicalTrials) | ||||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Centre Cardiologique du Nord - 93207 - Saint Denis - France | Olivier PIOT, MD | Contact (sur clinicalTrials) | |||
| Centre Hospitalier d'Aix en provence - 13616 - Aix-en-Provence - France | Jérôme TAIEB, MD | Contact (sur clinicalTrials) | |||
| CHU Amiens-Picardie-Site sud - 80054 - Amiens - France | Otilia BUICIUC, MD | Contact (sur clinicalTrials) | |||
| CHU de Nantes - 44093 - Nantes - France | Vincent PROBST, MD, PhD | Contact (sur clinicalTrials) | |||
| CHU de Rouen - 76000 - Rouen - France | Frédéric ANSELME, MD, PhD | Contact (sur clinicalTrials) | |||
| CHU Grenoble Alpes - 38700 - La Tronche - France | Pascal DEFAYE, MD, PhD | Contact (sur clinicalTrials) | |||
| CHU Poitiers - 86021 - Poitiers - France | Rodrigue Garcia, MD, PhD | Contact (sur clinicalTrials) | |||
| CHU Strasbourg - 67200 - Strasbourg - France | Laurence JESEL-MOREL, MD, PhD | Contact (sur clinicalTrials) | |||
| Clinique Pasteur - 31076 - Toulouse - France | Serge BOVEDA, MD, PhD | Contact (sur clinicalTrials) | |||
| Groupement d'Hôpitaux de l'Institut Catholique de Lille - 59462 - Lomme - France | Aymeric MENET, MD | Contact (sur clinicalTrials) | |||
| Hôpital de Brabois - 54710 - Nancy - France | Hugues BLANGY, MD | Contact (sur clinicalTrials) | |||
| Hôpital de La Timone - 13385 - Marseille - France | Jean Claude DEHARO, MD, PhD | Contact (sur clinicalTrials) | |||
| Hôpital Pitié-Salpétrière - 75013 - Paris - France | Estelle GANDJBAKHCH, MD, PhD | Contact (sur clinicalTrials) | |||
| Hôpital Pontchaillou - 35033 - Rennes - France | Vincent GALAND, MD | Contact (sur clinicalTrials) | |||
| Hôpital Privé du Confluent - 44277 - Nantes - France | Daniel GRAS, MD | Contact (sur clinicalTrials) | |||
| Hôpital Trousseau - 37170 - Tours - France | Laurent FAUCHIER, MD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- ≥70 years old,
- Left ventricular ejection fraction ≤ 35%
- NYHA class II or III
- Heart failure HFOT ≥ 3 months
- Providing informed consent
- Affiliated to a French Health Insurance system.
- ≥70 years old,
- Left ventricular ejection fraction ≤ 35%
- NYHA class II or III
- Heart failure HFOT ≥ 3 months
- Providing informed consent
- Affiliated to a French Health Insurance system.
- Enrolled in or planning to enroll in a conflicting interventional trial
- Prior unstable sustained ventricular arrhythmia requiring external cardioversion
- Myocardial infarction within the 40 days
- Coronary artery intervention (catheter or surgical) within 90 days
- History of syncope in the previous 6 months
- Advanced cerebrovascular disease
- Cognitive impairment leading to the incapacity of consent
- Any disease other than cardiac disease (e.g. cancer, uremia, liver failure),
associated with a likelihood of survival less than 1 year.
- Patient under tutorship, curatorship, or legal safeguard
- Persons deprived of their liberty by judicial or administrative decision (prisoner)