Informations générales (source: ClinicalTrials.gov)
Comparison of Scores for Early Brain Damage Assessment at Intensive Care Unit Admission After Cardiac Arrest (AfterROSC2)
Observational
AfterROSC (Voir sur ClinicalTrials)
novembre 2022
décembre 2025
29 juin 2024
Even in patients with successful return of spontaneous circulation (ROSC), outcome after
cardiac arrest remains poor. The overall in-hospital survival rate widely varies both
worldwide and across communities, from 1 to 4 folds according to circumstances of arrest
and post-resuscitation interventions. Several studies have already shown that early
interventions performed after ROSC, such as treatment of the cause, targeted temperature
management, optimal hemodynamic management and extra-corporeal life support in selected
patients, could improve the outcome in post-cardiac arrest patients. However, the
decision process regarding the allocation of these resources, in parallel with the
management of patients' proxies, remains a complex challenge for physicians facing these
situations. Consequently, several prediction models and scores have been developed in
order to stratify the risk of unfavorable outcome and to discriminate the best candidates
for post-resuscitation interventions. Overall, several scores exist, but external
validation are lacking and direct comparisons are needed to assess relative interest of
scoring systems. Indeed, establishing the optimal scoring system is crucial, for optimal
treatment allocation and appropriate information to relatives.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Cochin | Alain Cariou | Contact (sur clinicalTrials) | |||
| CH DE VERSAILLES SITE ANDRE MIGNOT | Marine Paul | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| CHU Nantes - Nantes - Pays De Loire - France | Jean Baptiste Lascarrou | Contact (sur clinicalTrials) | |||
| Clinique Ambroise Paré - Neuilly-sur-Seine - France | Guillaume Geri | Contact (sur clinicalTrials) | |||
| Hopital Jacques Cartier - Massy - France | Wulfran Bougouin | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- all adult patients, major, admitted to intensive care after cardiac arrest (after
both in and out-of hospital cardiac arrest),
- comatose (defined by Glasgow score ≤ 8) on admission,
- all adult patients, major, admitted to intensive care after cardiac arrest (after
both in and out-of hospital cardiac arrest),
- comatose (defined by Glasgow score ≤ 8) on admission,
- cardiac arrest occurring intra-hospital,
- minor patient,
- major patient under guardianship,
- protected persons,
- prior inclusion in the study