Informations générales (source: ClinicalTrials.gov)
National Cohort of Patients With Cowden's Disease and With a Constitutional Alteration of the PTEN Gene for the Prospective Assessment of the Risk of Cancer.
Observational
Institut Bergonié (Voir sur ClinicalTrials)
février 2023
janvier 2048
12 septembre 2025
This is a multicentric, observational, retrospective and prospective study, aiming to
estimate the risk of cancer occurrence in subjects carrying a PTEN mutation, based on the
constitution of a national cohort.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| CLCC INSTITUT CURIE | 10/04/2025 13:12:23 | Contact (sur clinicalTrials) | |||
| CLCC RENE HUGUENIN INSTITUT CURIE | 10/04/2025 13:12:05 | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Institut Bergonié, Comprehensive Cancer Center - Bordeaux - France | Contact (sur clinicalTrials) | ||||
Critères
Tous
Inclusion Criteria:
1. Male or female.
2. Adult or child without age limit.
3. Carrier of a constitutional or mosaic alteration of the PTEN gene established and/or
confirmed by the Institut Bergonié's genetics laboratory, following a request for
molecular diagnosis made between 1997 and 2027.
4. Participant informed of his genetic diagnosis.
5. Participant informed and not having expressed non-opposition to participate in the
research.
6. Participant affiliated to a French social security system in accordance with French
law on research involving the human person.
1. Male or female.
2. Adult or child without age limit.
3. Carrier of a constitutional or mosaic alteration of the PTEN gene established and/or
confirmed by the Institut Bergonié's genetics laboratory, following a request for
molecular diagnosis made between 1997 and 2027.
4. Participant informed of his genetic diagnosis.
5. Participant informed and not having expressed non-opposition to participate in the
research.
6. Participant affiliated to a French social security system in accordance with French
law on research involving the human person.
1. Participant under guardianship or curatorship. Exception: a participant with autism
may be included in the study.
2. Persons deprived of their liberty by a judicial or administrative decision.
3. Persons under psychiatric care, persons admitted to a health or social establishment
for purposes other than research; Exception: a participant with autism may be
included in the study.