Informations générales (source: ClinicalTrials.gov)
Compassion Focused Therapy (CFT) for the Reduction of the Internalized Stigma of Mental Disorders: a Multi-center, Prospective, Randomized, Controlled Study (COMPASS)
Interventional
N/A
University Hospital, Strasbourg, France (Voir sur ClinicalTrials)
avril 2023
mars 2028
20 août 2024
People with mental disorders face frequent stigmatizing attitudes and behaviors from
others . In response to this, they tend to isolate themselves, with the risk of impeding
care and the process of recovery and integration into society . Stigmatization can also
be assimilated by patients themselves - i.e. self-stigma. Self-stigma is involved in
diminished coping skills that lead to social avoidance and difficulties in adhering to
care . Reducing self-stigma and its emotional corollary, shame, is thus crucial to
attenuate the disability associated with mental illness. Shame is inherent to self-stigma
and leads to difficulties in adhering to care as well as greater severity of clinical
presentations . Compassion Focused Therapy (CFT) is a third wave cognitive behavioral
therapy that targets shame reduction and hostile self-to-self relationship and allows for
symptom improvement while increasing self-compassion, a major resilience factor .
Although shame is a prominent part of the concept of self-stigma, the efficacy of CFT has
never been evaluated in individuals with high levels of self-stigma.
In this study, the investigators will evaluate the efficacy and acceptability of a group
based CFT program on decreasing self-stigma, compared to treatment as usual (TAU) and a
psychoeducation program whose efficacy has been assessed in a previous trial.
Etablissements
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| Ch Le Vinatier - 69678 - Bron - France | Nicolas FRANCK, MD | Contact (sur clinicalTrials) | |||
| CHU de Clermont-Ferrand, Hôpital Gabriel Montpied, Service de Psychiatrie B - 63003 - Clermont-Ferrand - France | Pierre-Michel LLORCA, MD | Contact (sur clinicalTrials) | |||
| CHU de Montpellier, Psychiatrie d'adultes, Hôpital la Colombière - 34295 - Montpellier - France | Delphine CAPDEVIELLE, MD | Contact (sur clinicalTrials) | |||
| Etablissement Public de Santé Mentale (EPSM) de la Marne, Site Pierre-Briquet, Unité de réhabilitation psychosociale - 51100 - Reims - France | Martina TRAYKOVA- BOGOVA, MD | Contact (sur clinicalTrials) | |||
| Pôle de Psychiatrie Adulte, Hôpital Charles Perrens - 33076 - Bordeaux - France | David MISDRAHI, MD | Contact (sur clinicalTrials) | |||
| Pôle Hospitalo-Universitaire de Psychiatrie d'adultes et d'addictologie du Grand Nancy, Centre Psychothérapique de Nancy - 54520 - Laxou - France | David MASSON, MD | Contact (sur clinicalTrials) | |||
| Service de Psychiatrie, Hôpital Civil, Hôpitaux Universitaires de Strasbourg - 67091 - Strasbourg - France | Luisa WEINER, MD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
1. Patient ≥18 years of age
2. Patient informed of the results of the preliminary medical examination
3. Patient affiliated to a social health insurance plan (beneficiary or beneficiary's
family)
4. Patient with one or several diagnoses of chronic psychiatric disorder
(schizophrenia, schizoaffective disorder, bipolar disorder, recurrent major
depression, borderline personality disorder) or a neurodevelopmental disorder
(autism spectrum disorder) treated as an outpatient or in a day hospital
5. CGI-Severity score<6 assessed by the psychiatrist (Berk et al., 2008) ISMI score
indicating moderate to high self-stigma (>2.5; Lysaker et al., 2007)
1. Patient ≥18 years of age
2. Patient informed of the results of the preliminary medical examination
3. Patient affiliated to a social health insurance plan (beneficiary or beneficiary's
family)
4. Patient with one or several diagnoses of chronic psychiatric disorder
(schizophrenia, schizoaffective disorder, bipolar disorder, recurrent major
depression, borderline personality disorder) or a neurodevelopmental disorder
(autism spectrum disorder) treated as an outpatient or in a day hospital
5. CGI-Severity score<6 assessed by the psychiatrist (Berk et al., 2008) ISMI score
indicating moderate to high self-stigma (>2.5; Lysaker et al., 2007)
6. Patient in an exclusion period determined by a previous or ongoing study
7. Patient participating in an interventional study involving psychotherapy or an
experimental drug
8. Patient in acute episode of their disorder according to the CGI Severity score
9. Patient in a medical emergency or immediate life-threatening situation
10. Patients with an intellectual disability (IQ<70) estimated via the fNART (Mackinnon
& Mulligan, 2005)
12. Legal issues: care under constraint or patient deprived of freedom because of a
judicial measure 13. Patient who does not speak and read French sufficiently