Informations générales (source: ClinicalTrials.gov)
Impact of ECMO Cannula Chlorhexidine-impregnated Dressings to Decrease Extracorporeal Membrane Oxygenation-cannula Related Infection Rate (DRESSING-ECMO)
Interventional
N/A
Assistance Publique - Hôpitaux de Paris (Voir sur ClinicalTrials)
février 2023
décembre 2025
05 mai 2025
The Dressing-ECMO trial is a prospective, open-label, multicenter, controlled trial
randomizing patients who received percutaneous ECMO to cannula chlorhexidine-impregnated
dressing vs standard dressing. The study goal is to determine if cannula
chlorhexidine-impregnated dressings can reduce the number of cannula major-related
infections with or without bloodstream infection
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| HOPITAL FOCH | Guillaume TACHON | 05/05/2025 07:12:13 | Contacter | ||
Critères
Tous
Inclusion Criteria:
- Patients with cardiogenic shock or refractory acute respiratory distress syndrome
ECMO VA or VV ECMO for less than 24 hours.
- ECMO duration > 48 hours
- Obtained written informed consent from the trusted person or family member/relative.
Depending on the emergency consent, randomization may take place and consent of the
trusted person/relative/family will be obtained as soon as possible. The patient
will be asked to give his/her consent for the continuation of the trial when hid/her
condition will allow.
- Affiliation to a social security system (excluding state medical aid)
- Patients with cardiogenic shock or refractory acute respiratory distress syndrome
ECMO VA or VV ECMO for less than 24 hours.
- ECMO duration > 48 hours
- Obtained written informed consent from the trusted person or family member/relative.
Depending on the emergency consent, randomization may take place and consent of the
trusted person/relative/family will be obtained as soon as possible. The patient
will be asked to give his/her consent for the continuation of the trial when hid/her
condition will allow.
- Affiliation to a social security system (excluding state medical aid)
- Age <18 years
- Initiation of ECMO for more than 24 hours
- Surgical (i.e. non percutaneous) cannulation
- Patient moribund on day of randomization, SAPS II >90
- Known allergy to chlorhexidine
- Antibiotic prophylaxis at ECMO cannulation