Informations générales (source: ClinicalTrials.gov)
Comparison of the Two-year Efficacy of Three Exercise Rehabilitation Strategies on Dyspnea in Patients Who Presented With Secondary Respiratory Distress Syndrome Secondary to Severe COVID-19 Pneumonia (RECOVER_FU)
Observational
Fondation Hôpital Saint-Joseph (Voir sur ClinicalTrials)
août 2023
décembre 2024
29 juin 2024
Dyspnea is defined by a subjective sensation of respiratory discomfort, the intensity of
which varies according to the terrain, the anamnesis and the cause. Resuscitation is
associated with many causes of dyspnea, including initial distress, mechanical
ventilation, or after-effects following the pathology and its management.
Respiratory distress is the most severe form of impaired lung function. It is the first
cause of hospitalization in intensive care. This distress, indicative of the failure of
the respiratory system, is always severe and potentially fatal. It therefore constitutes
an absolute therapeutic emergency. Dyspnea is often the revealing symptom of the
condition and the urgency surrounding its management is an additional factor of concern
for the patient. As a result, dyspnea is a pejorative element associated with severity or
even death.
In patients surviving the initial condition, dyspnea persists and can be found months or
even years later, despite the initial rehabilitation. It is strongly associated with
anxiety or even the fear of dying and contributes to the occurrence of post-traumatic
stress syndromes. This persistent sensation of respiratory discomfort, limiting the
patient's autonomy in his activities of daily living, seems to be able to reduce his
quality of life. In addition, the perpetuation of this dyspnea could favor a spiral of
deconditioning causing a progressive deterioration of the cardio-respiratory system
justifying new hospitalizations.
In patients with chronic respiratory failure, exercise rehabilitation supervised by
hysiotherapists allows, in addition to improving autonomy, a significant reduction in
dyspnoea, thus increasing the quality of life of these patients.
The main objective of this study is to evaluate the effect at 2 years of 3 modes of
management of dyspnea: exercise rehabilitation, standard physiotherapy and "usual care"
on post-resuscitation dyspnea in patients with presented with severe COVID-19.
Etablissements
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Cochin | Frédéric PENE, MD | Contact (sur clinicalTrials) | |||
| CH DE VERSAILLES SITE ANDRE MIGNOT | Alexis FERRE, MD | Contact (sur clinicalTrials) | |||
| GH PARIS SITE SAINT JOSEPH | Christophe Romanet | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Centre Hospitalier Victor Dupouy - Argenteuil - France | Gaetan PLANTEFEVE, MD | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
Patients in the RECOVER study (NCTT04569266):
- Patient ≥ 18 years old
- Patient meeting the inclusion criteria for this study (see appendix 1)
- Patient more than 2 years from their release from intensive care
- French-speaking patient
- Patient not objecting to their participation in this research
Usual care patients
- Patient ≥ 18 years old
- Patient having presented a respiratory infection by SARS-Cov-2 confirmed
biologically in the laboratory by PCR or any other commercial or public health test
or diagnosed by CT scan
- Patient who was under invasive mechanical ventilation during a stay in intensive
care in the center of Versailles for more than 48 consecutive hours following
infection by SARS-Cov-2 between 01/03/2020 and 26/01/2022
- Patient more than 2 years from their release from intensive care
- French-speaking patient
- Patient not objecting to their participation in this research
Patients in the RECOVER study (NCTT04569266):
- Patient ≥ 18 years old
- Patient meeting the inclusion criteria for this study (see appendix 1)
- Patient more than 2 years from their release from intensive care
- French-speaking patient
- Patient not objecting to their participation in this research
Usual care patients
- Patient ≥ 18 years old
- Patient having presented a respiratory infection by SARS-Cov-2 confirmed
biologically in the laboratory by PCR or any other commercial or public health test
or diagnosed by CT scan
- Patient who was under invasive mechanical ventilation during a stay in intensive
care in the center of Versailles for more than 48 consecutive hours following
infection by SARS-Cov-2 between 01/03/2020 and 26/01/2022
- Patient more than 2 years from their release from intensive care
- French-speaking patient
- Patient not objecting to their participation in this research
- Patient under guardianship or curatorship
- Patient deprived of liberty
- Patient under legal protection