Informations générales (source: ClinicalTrials.gov)
A Prospective, Non-interventional Study (NIS) With Trastuzumab Deruxtecan For Patients With HER2-low Expressing Unresectable and/or Metastatic Breast Cancer Accompanied By a Disease Registry of Patients Treated With Conventional Chemotherapy (DESTINY Breast Respond HER2-low Europe)
Observational
Daiichi Sankyo Europe, GmbH, a Daiichi Sankyo Company (Voir sur ClinicalTrials)
octobre 2023
septembre 2028
08 avril 2025
Trastuzumab deruxtecan (T-DXd) as monotherapy is indicated for the treatment of adult
patients with unresectable or metastatic HER2-low breast cancer who have received prior
chemotherapy in the metastatic setting or developed disease recurrence during or within 6
months of completing adjuvant chemotherapy.
Etablissements
| Les établissements d'Île-de-France ayant mis à jour leurs données Origine et niveau de fiabilité des données | |||||
|---|---|---|---|---|---|
| AP-HP - Hôpital Henri Mondor-Albert Chenevier | Zineb SELLAM | 07/03/2025 14:58:34 | Contacter | ||
| CLCC INSTITUT CURIE | 10/04/2025 13:12:23 | Contact (sur clinicalTrials) | |||
| CLCC RENE HUGUENIN INSTITUT CURIE | 10/04/2025 13:12:05 | Contact (sur clinicalTrials) | |||
| HOPITAL FOCH | Asmahane BENMAZIANE TEILLET | 14/04/2025 07:01:42 | Contacter | ||
| Les établissements d'Île-de-France dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| AP-HP - Hôpital Europeen Georges Pompidou | Principal Investigator | Contact (sur clinicalTrials) | |||
| GH PARIS SITE SAINT JOSEPH | Principal Investigator | Contact (sur clinicalTrials) | |||
| GRPE HOSP DIACONESSES-CROIX ST-SIMON | Principal Investigator | Contact (sur clinicalTrials) | |||
| Les établissements sans correspondance certaine dans le répertoire FINESS dont les données sont issues de ClinicalTrials.gov Origine et niveau de fiabilité des données | |||||
| Centre Antoine Lacassagne - 06100 - Nice - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre de cancerologie de la Sarthe - 72100 - Le Mans - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre d'oncologie Saint-Yves - 56000 - Vannes - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Eugene Marquis - 35042 - Rennes - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Francois Baclesse - 14000 - Caen - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Georges Francois Leclerc - 21000 - Dijon - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Hospitalier de Niort - 79000 - Niort - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Hospitalier de Pau - 64000 - Pau - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Hospitalier de Sens - 89108 - Sens Cédex - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Hospitalier de Troyes - 10000 - Troyes - France | Contact (sur clinicalTrials) | ||||
| Centre Hospitalier Emile Roux - 43000 - Le Puy-en-Velay - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre hospitalier Fleyriat - 01012 - Bourg-en-Bresse - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Hospitalier William Morey - 71321 - Chalon-sur-Saône - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Jean Perrin - 63011 - Clermont-Ferrand - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Léonard de Vinci - 59187 - Dechy - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Médical ONCOGARD - 30029 - NÎMES Cedex 9 - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Centre Oscar Lambret - 59000 - Lille - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CH Cholet - 49300 - Cholet - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CH Cote Basque - 64100 - Bayonne - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CH Metropole Savoie - 73000 - Chambéry - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHI Frejus Saint Raphael - 83600 - Fréjus - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHR Metz Thionville - 57100 - Thionville - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHU Amiens Picardie - 80000 - Amiens - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHU de Limoges - 87042 - Limoges - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Chu Jean Minjoz Besancon - 25000 - Besançon - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHU Lille - 59000 - Lille - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHU Martinique - 97261 - Fort De France Cedex - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHU Poitiers - 86000 - Poitiers - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| CHU Réunion Site Sud - 97460 - Saint-Paul - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Clinique Belharra - 64100 - Bayonne - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Clinique Clementville - 34070 - Montpellier - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Clinique de l'Europe - 80090 - Amiens - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Clinique Mathilde - 76100 - Rouen - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Clinique Saint Hilaire - 76000 - Rouen - France | Contact (sur clinicalTrials) | ||||
| Clinique Tivoli-Ducos - 33000 - Bordeaux - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| GH Havre - 76920 - Montivilliers - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Groupe Hospitalier Mutualiste (GHM) de Grenoble - Institut Daniel Hollard (IDH) - 38000 - Grenoble - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Groupe Hospitalier privé Ambroise Pare Hartmann - 92200 - Neuilly-sur-Seine - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| HIA Sainte-Anne - 83000 - Toulon - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hopital Americain de Paris - 92200 - Neuilly-sur-Seine - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hôpital Franco-Britannique Cognac Jay - 92300 - Levallois-Perret - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hôpital Jean Mermoz - 69008 - Lyon - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hôpital Privé d'Antony - 92160 - Antony - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hopital Prive Drome Ardeche - 26000 - Valence - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hôpital Prive Le Bois - 59000 - Lille - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hôpital Privé les Bonnettes - 62000 - Arras - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hôpital-Clinique Claude Bernard - 57070 - Metz - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Hospices Civils De Lyon - 69002 - Lyon - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Institut De Cancerologie De Lorraine - 54519 - Vandœuvre-lès-Nancy - France | Contact (sur clinicalTrials) | ||||
| Institut De Cancerologie Paris Nord - 95200 - Sarcelles - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Institut du Cancer Avignon Provence - 84918 - Avignon - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Institut Godinot - 51100 - Reims - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| La Tronche - CHU Grenoble - 38700 - La Tronche - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Médipôle Hôpital Mutualiste - 69100 - Villeurbanne - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Nouvelle Clinique Des Dentellières - 59300 - Valenciennes - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Pole Sante Leonard De Vinci - 37170 - Chambray-lès-Tours - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Polyclinique Courlancy - 51100 - Reims - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Polyclinique De Blois - 41260 - La Chaussee Saint Victor - France | Principal Investigator | Contact (sur clinicalTrials) | |||
| Polyclinique St Côme - 60200 - Compiègne - France | Principal Investigator | Contact (sur clinicalTrials) | |||
Critères
Tous
Inclusion Criteria:
- Adult patient (age ≥ 18 years) with histological or cytological confirmed diagnosis
of unresectable and/or mBC
- Documented HER2-low status (IHC1+, IHC2+/ISH-)
- Patients who have received prior chemotherapy in the metastatic setting or patients
who have developed disease recurrence during or within 6 months of completing
adjuvant chemotherapy
- Decision to newly initiate therapy of T-DXd or conventional chemotherapy according
to the physicians choice per SmPC
- Written and signed Informed Consent to participate in the study
- Adult patient (age ≥ 18 years) with histological or cytological confirmed diagnosis
of unresectable and/or mBC
- Documented HER2-low status (IHC1+, IHC2+/ISH-)
- Patients who have received prior chemotherapy in the metastatic setting or patients
who have developed disease recurrence during or within 6 months of completing
adjuvant chemotherapy
- Decision to newly initiate therapy of T-DXd or conventional chemotherapy according
to the physicians choice per SmPC
- Written and signed Informed Consent to participate in the study
- Pregnancy or breastfeeding
- Patients who at time of data collection for this study are participating in or have
participated in an interventional study that remains blinded.
No specific exclusion criteria are defined, as patients will be treated according to the
proposed indication statements in the SmPC.